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Coya Therapeutics (COYA) investor relations material
Coya Therapeutics H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 27th Annual Global Investment Conference summary10 Sep, 2025
Vision and scientific approach
Focused on transforming neurodegenerative diseases like ALS and FTD into manageable conditions by targeting neuroinflammation through regulatory T cell (Treg) therapies.
Believes that increasing and sustaining Treg numbers and function can halt disease progression.
Early clinical and biomarker data support the approach, showing stabilization or improvement in patient scores.
Lead program and clinical progress
Lead candidate COIA-302 combines low-dose interleukin-2 with CTLA-4 to address both adaptive and innate immune systems.
Phase 2b pivotal trial in ALS (120 patients) to begin dosing in Q4, with FDA green light and NILS consortium support.
Investigator-initiated studies showed no decline in ALSFRS scores over six months and minimal decline over one year, contrasting with expected rapid deterioration.
Biomarker data confirm increased Treg function and reduced oxidative stress during treatment.
Partnerships and financial outlook
Commercialization partnership with Dr. Reddy’s Laboratories for ALS indication, providing non-dilutive funding and global market access.
$700M partnership includes milestone payments, with $4.2M received at IND approval and another $4.2M due at first patient dosing.
Retained rights for other indications and strong collaboration with Houston Methodist for basic science research.
Dr. Reddy's partnership: non-financial benefits?
Why target nonfluent aphasia in FTD study?
Novo Nordisk data: impact on COIA-303 strategy?
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Next Coya Therapeutics earnings date
Q3 20255 Nov, 2025
Next Coya Therapeutics earnings date
Q3 20255 Nov, 2025
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Frequently asked questions
Coya Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing proprietary therapies that enhance the function of regulatory T cells (Tregs). The company’s therapeutic platforms include Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy. These therapies are aimed at treating neurodegenerative, autoimmune, and metabolic diseases. Coya Therapeutics is headquartered in Houston, Texas, and its shares are listed on the NASDAQ.
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