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Cryoport (CYRX) investor relations material

Cryoport Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary4 Nov, 2025

Executive summary

  • Q3 2025 revenue grew 15.4% year-over-year to $44.2 million, driven by double-digit growth in both Life Sciences Services and Products, and strong commercial cell & gene therapy performance.

  • Commercial cell & gene therapy revenue rose 36% year-over-year to $8.3 million, supporting 19 commercial therapies and 745 global clinical trials.

  • Gross margin improved to 48.2% from 45.5% in Q3 2024, reflecting operational efficiencies and favorable product mix.

  • Completed divestiture of CRYOPDP business to DHL, resulting in a significant gain and a strategic partnership to enhance EMEA and APAC growth.

  • Expanded global presence with a new supply chain center in Paris and launched next-generation dry vapor shippers with integrated monitoring.

Financial highlights

  • Life Sciences Services revenue grew 16% year-over-year to $24.3 million; Products revenue increased 15% to $20.0 million; BioStorage/BioServices up 21% to $4.8 million.

  • Gross margin for Q3 2025 was 48.2%, with services at 49.7% and products at 46.4%.

  • Adjusted EBITDA from continuing operations was negative $0.6 million for Q3 2025, a significant improvement over prior periods.

  • Cash, cash equivalents, and short-term investments totaled $421.3 million as of September 30, 2025.

  • Net income for the first nine months of 2025 was $89.9 million, primarily due to the CRYOPDP sale.

Outlook and guidance

  • Full-year 2025 revenue guidance raised to $170–$174 million, representing 8–11% growth over the prior year.

  • Anticipates positive adjusted EBITDA as early as year-end 2025, with significant operating leverage expected in 2026–2027.

  • Long-term growth rate expected to align with the cell and gene therapy market.

  • Guidance reflects caution due to macroeconomic factors, supply chain constraints, inflation, and the ongoing U.S. government shutdown.

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Frequently asked questions

Cryoport Inc is a global provider of temperature-controlled supply chain solutions, primarily serving the life sciences industry. The company specializes in supporting the logistics of temperature-sensitive materials, including those vital for cell and gene therapies, biopharmaceuticals, in vitro fertilization (IVF), surrogacy, and animal health sectors. Its services are crucial in maintaining the integrity of biological samples and products through the use of advanced cryogenic logistics solutions. Cryoport manages these shipments through its Cryoportal, a cloud-based logistics management platform that ensures the secure and efficient transport of life sciences commodities worldwide. The platform offers comprehensive management of shipment processes, including order entry, document preparation, customs documentation, courier management, real-time tracking, and regulatory compliance. The company is headquartered in Nashville, TN, and its shares are listed on the Nasdaq.

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