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Cryoport (CYRX) investor relations material

Cryoport Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary5 Aug, 2025

Executive summary

  • Q2 2025 revenue rose 14–14.5% year-over-year to $45.5M, with double-digit growth in Life Sciences Services and Products, and notable gains in BioStorage/BioServices and BioLogistics Solutions.

  • Strategic partnership with DHL Group completed, including the divestiture of CRYOPDP, resulting in a $116.7M–$117.4M gain and enhanced global biologistics capabilities.

  • Supported 728 active clinical trials and 18 commercial therapies globally as of June 30, 2025, with 82 in Phase III.

  • Commercial Cell & Gene Therapy revenue increased 32–33% year-over-year to $8.7M, with BioStorage/BioServices up 28%.

  • Net income for Q2 2025 was $105.2M, primarily due to the CRYOPDP sale gain.

Financial highlights

  • Gross margin improved to 47% in Q2 2025, up from 44.5% in Q2 2024.

  • Adjusted EBITDA from continuing operations improved to negative $0.9M from negative $5.6M year-over-year.

  • Life Sciences Services revenue was $24.4M (54% of total), up 21% year-over-year; Products revenue was $21.1M, up 8%.

  • Cash, cash equivalents, and short-term investments totaled $426M as of June 30, 2025.

  • Net income margin for Q2 2025 was 231.3%, driven by the one-time CRYOPDP gain.

Outlook and guidance

  • Full-year 2025 revenue guidance reaffirmed at $165M–$172M, representing 5–10% year-over-year growth.

  • Guidance reflects a $2M revenue impact from a client’s temporary therapy pause and no expected market recovery in China for 2025.

  • Management expects cost reduction and capital realignment to return the business to positive adjusted EBITDA during 2025.

  • Guidance for 2026 will be provided at year-end; outlook includes expectations for additional BLA/MAA filings and approvals.

  • Gross margins expected to remain relatively flat in the second half, with a long-term goal of exceeding 55% gross margin and 30% adjusted EBITDA margin.

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Frequently asked questions

Cryoport Inc is a global provider of temperature-controlled supply chain solutions, primarily serving the life sciences industry. The company specializes in supporting the logistics of temperature-sensitive materials, including those vital for cell and gene therapies, biopharmaceuticals, in vitro fertilization (IVF), surrogacy, and animal health sectors. Its services are crucial in maintaining the integrity of biological samples and products through the use of advanced cryogenic logistics solutions. Cryoport manages these shipments through its Cryoportal, a cloud-based logistics management platform that ensures the secure and efficient transport of life sciences commodities worldwide. The platform offers comprehensive management of shipment processes, including order entry, document preparation, customs documentation, courier management, real-time tracking, and regulatory compliance. The company is headquartered in Nashville, TN, and its shares are listed on the Nasdaq.

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