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Investor Relations14 Oct 2025
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CureVac (CVAC) investor relations material
CureVac Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary15 Aug, 2025
Executive summary
Entered into a definitive agreement for acquisition by BioNTech, combining two German mRNA leaders to accelerate global mRNA-based treatments.
Settled all pending U.S. patent litigation with Pfizer/BioNTech regarding mRNA COVID-19 vaccines, with a framework for resolving disputes outside the U.S. post-acquisition.
Received EMA clearance for a clinical trial of CVHNLC, an off-the-shelf immunotherapy for squamous non-small cell lung cancer; glioblastoma program remains on track for H2 2025 data.
Financial highlights
Cash and cash equivalents stood at €392.7 million as of June 30, 2025, down from €481.7 million at year-end 2024.
Revenues for Q2 and H1 2025 were €1.2 million and €2.1 million, down 91% and 92% year-over-year, mainly due to restructuring of the GSK partnership and lower sales to CRISPR Therapeutics.
Operating loss for Q2 and H1 2025 was €61.7 million and €116.5 million, improving from €73.6 million and €146.9 million in the prior year periods.
Pre-tax loss for Q2 and H1 2025 was €60.0 million and €111.6 million, compared to €71.2 million and €141.1 million in the same periods of 2024.
Outlook and guidance
Cash runway is expected to extend into 2028, supported by cost reductions and strategic restructuring.
Phase 1 data for the glioblastoma program (CVGBM) expected in H2 2025; IND submission for infectious disease candidate planned for H2 2025, with Phase 1 trial in H1 2026.
Patent licensing post-BioNTech acquisition?
Why did H1 2025 cash outflow decrease?
CVGBM Phase 1 Part B data expectations?
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Q3 202511 Nov, 2025
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Frequently asked questions
CureVac N.V., a clinical-stage biopharmaceutical company, focuses on developing various transformative medicines based on messenger ribonucleic acid (mRNA). Its product candidates are also developed for prophylactic vaccines, cancer immunotherapy and other therapeutic areas. The company's lead product candidate is CVnCoV that is in Phase I human clinical trials to protect against coronaviruses, including the SARS-CoV-2 virus. It also develops additional prophylactic vaccine antibiotics, including CV301, which is in Phase II clinical trials for treating non-small cell lung cancer and cervical cancer; CV9202 in preclinical stage for treating melanoma and prostate cancer; and CV8102 preclinical stage for treating breast and pancreatic cancers.
The company's mRNA therapeutics have demonstrated their potential to treat cancers through the triggering of intracellular immune responses. CureVac N.V. operates in the United States, Germany, and internationally. The company was formerly known as Curevac GmbH and changed its name to CureVac N.V. in December 2016.
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