Cybin (CYBN) investor relations material

Key themes and industry insights

• Mental health conditions affect over a billion people globally and are projected to cost the global economy $6 trillion by 2030.

• Innovations span psychedelics, digital tools, built environment, and funding models to address mental health.

• Emphasis on integrating brain and body health, prevention, and early intervention.

• Equity and access remain major challenges, especially in rural and underserved communities.

• Policy, reimbursement, and cultural change are critical to scaling effective solutions.

Advances in treatment and technology

• Psychedelic compounds like CYB003 (depression) and CYB004 (anxiety) show promise, with FDA breakthrough designation and durable results.

• Digital tools and wearables enable self-agency, real-time symptom tracking, and scalable interventions.

• Digital diaries and apps can improve outcomes even before clinical appointments, as shown in studies with depression patients.

• Initiatives like BD Squared aim to define biomarkers and mechanisms for bipolar disorder using digital engagement.

Built environment and social determinants

• Green spaces and biophilic design in urban areas reduce depression and anxiety symptoms.

• Simple environmental changes, such as artwork in psychiatric settings, can lower medication use and improve outcomes.

• Projects like UC San Diego's lived-learn neighborhood demonstrate measurable reductions in student depression.

• Cities like New York leverage design trusts and sociocultural infrastructure to promote mental health.