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Cybin (CYBN) investor relations material
Cybin Jefferies London Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Jefferies London Healthcare Conference 2025 summary17 Nov, 2025
Industry context and unmet needs
Traditional antidepressants have limited efficacy and challenging side effects, with two-thirds of patients not responding initially.
Interventional psychiatry clinics have grown to 8,000 in the U.S., but access is limited by frequent treatment requirements.
New approaches aim to reduce administrative burden and improve access for mood and behavioral disorders.
Clinical development and pipeline
Two proprietary assets, CYB003 and CYB004, are in late-stage development, protected by over 100 granted patents and 250 pending.
CYB003 is in Phase 3 for adjunctive Major Depressive Disorder (MDD), with top-line data expected in Q4 next year.
EMBRACE, a second Phase 3 study for CYB003, has just initiated, with enrollment starting this quarter.
CYB004 targets Generalized Anxiety Disorder (GAD) and has completed Phase 2 enrollment, with data expected in Q1 next year.
Differentiation and innovation
CYB003 is a deuterated psilocybin analog designed for oral dosing, fitting within an eight-hour clinical day.
CYB004 is a deuterated DMT analog optimized for intramuscular injection, extending effects to under two hours for convenience and scalability.
Both assets address large U.S. patient populations (20 million each for MDD and GAD) and leverage a common commercialization platform.
Managing subjective effects and efficacy link
Impact on clinic capacity and patient access
Payer strategy for adjunctive MDD and flexibility
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Next Cybin earnings date
Q3 20269 Feb, 2026
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Frequently asked questions
Cybin Inc. is a clinical-stage biopharmaceutical company dedicated to developing psychedelic-based therapeutics. The company focuses on creating treatments for mental health conditions through innovative drug discovery platforms, drug delivery systems, and formulation approaches. Cybin is developing a range of proprietary psychedelic molecules, including CYB003, a deuterated psilocybin analog for major depressive disorder, and CYB004, a deuterated DMT molecule for generalized anxiety disorder. These efforts are part of Cybin's broader mission to address unmet needs in mental healthcare with novel therapeutic options. The company is headquartered in Toronto, Canada, and its shares are listed on the NYSE.
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