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Helus Pharma (HELP) investor relations material
Helus Pharma Q1 2027 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Appointed Michael Halstead as CEO to lead late-stage development and commercialization.
Completed enrollment in Phase 3 APPROACH study for HLP003 in MDD; topline data expected Q4 2026.
Advanced HLP004 for generalized anxiety disorder, with strong Phase 2 results and next study design due by end of Q3 2026.
Strengthened balance sheet with $50 million underwritten offering in June 2026.
Financial highlights
Cash totaled $166.4 million as of June 30, 2026.
Net loss was $47.8 million for Q1 2027, compared to $24.6 million in the same period last year.
Cash-based operating expenses were $37.5 million, up from $23.9 million year-over-year.
Cash flows used in operating activities were $37.1 million, compared to $29.5 million last year.
Increased expenses driven by advancement of HLP003 Phase 3 trials.
Outlook and guidance
Topline data for HLP003 Phase 3 APPROACH study expected in Q4 2026.
HLP004 next study design to be completed by end of Q3 2026.
HLP005 development candidate selection anticipated in second half of 2027.
- Phase III data for a differentiated adjunctive depression therapy is expected in Q4.HELP
Canaccord Genuity's 46th Annual Growth Conference - FDA guidance and trial rigor shape psychedelic therapy development as key programs advance toward pivotal data.HELP
TD Cowen 4th Annual Novel Mechanisms in Neuropsychiatry Summit 2024 - HLP003 and HLP004 show strong Phase 2 efficacy and safety, advancing toward pivotal trials.HELP
Corporate presentation - Net loss widened to $148M on higher R&D, but cash rose to $157M after major financings.HELP
Q4 2026 - Phase III data for a novel adjunctive MDD therapy expected by year-end, supporting 2028 NDA plans.HELP
7th Annual HCW Neuro Perspectives Hybrid Conference - Lead MDD therapy shows high durability and strong efficacy, with pivotal phase III data due in Q4.HELP
Jefferies Global Healthcare Conference 2026 - HLP003 and HLP004 show strong clinical results and IP protection, targeting major mental health needs.HELP
Corporate presentation - Phase II data showed rapid, durable anxiety relief and high remission rates with strong safety.HELP
Study result - 100% response and 71% remission at 12 months for 16mg; Phase 3 trials underway.HELP
Status Update
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