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Editas Medicine
Editas Medicine (EDIT) investor relations material
Editas Medicine Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q4 2025 earnings summary9 Mar, 2026
Executive summary
Lead candidate EDIT-401 showed over 90% mean LDL-C reduction in preclinical studies and is on track for IND/CTA submission by mid-2026.
First-in-human clinical trial in HeFH patients planned for late 2026, with early proof-of-concept data expected by year-end 2026.
Strong cash position with runway into Q3 2027 supports ongoing development milestones.
Financial highlights
Cash and cash equivalents were $146.6M as of December 31, 2025, down from $269.9M at year-end 2024.
Q4 2025 net loss was $5.6M ($0.06/share), a significant improvement from $45.4M ($0.55/share) in Q4 2024.
Full year 2025 net loss was $160.1M ($1.80/share), improved from $237.1M ($2.88/share) in 2024.
Q4 2025 revenues were $24.7M, down from $30.6M in Q4 2024; full year 2025 revenues were $40.5M, up from $32.3M in 2024.
Research and development expenses for 2025 decreased to $90.0M from $199.2M in 2024.
Outlook and guidance
IND/CTA submission for EDIT-401 expected by mid-2026.
First-in-human trial for HeFH patients to begin in 2026, with topline data anticipated in 2027.
Cash runway projected into Q3 2027, supporting planned milestones.
EDIT-401 preclinical vs clinical LDL-C reduction
Cash runway sufficiency for 2027 topline data
Drivers of the Q4 restructuring benefit
Partial view of Summaries dataset, powered by Quartr API
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Next Editas Medicine earnings date
Barclays 28th Annual Global Healthcare Conference12 Mar, 2026
Editas Medicine
Next Editas Medicine earnings date
Barclays 28th Annual Global Healthcare Conference12 Mar, 2026
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Frequently asked questions
Editas Medicine, a genome editing company, focuses on developing transformative genomic medicines to treat a range of serious diseases. The company seeks to address the fundamental flaws in existing approaches to genetic and infectious diseases by developing TALEN and CRISPR genome editing systems that function more efficiently than existing technologies. It has invented lymphocyte-directed gene therapy that uses CRISPR/Cas9 technology to manufacture a novel endonuclease. Editas Medicine, Inc. was incorporated in 2013 and is based in Cambridge, Massachusetts.
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