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Climb Bio (CLYM) investor relations material
Climb Bio Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Advanced clinical pipeline with lead candidates budoprutug (anti-CD19 mAb) in Phase 2 for pMN and Phase 1b/2a for ITP and SLE, and CLYM116 (anti-APRIL mAb) entering Phase 1 for IgA nephropathy, with initial data expected in 2026.
Regulatory clearance obtained for CLYM116 Phase 1 trial in IgA nephropathy; first dosing expected by year-end 2025 and initial data mid-2026.
No product revenue to date; operations funded by equity offerings and a $120M private placement in June 2024.
Leadership team expanded with new CFO, SVP of Technical Operations, and SVP of People & Workforce Strategy.
Financial highlights
Net loss of $12.9M for Q3 2025, or $0.19 per share, compared to $8.9M, or $0.13 per share, in Q3 2024.
Research and development expenses increased to $9.1M in Q3 2025 from $6.2M in Q3 2024.
General and administrative expenses rose to $5.8M in Q3 2025 from $5.5M in Q3 2024.
Cash, cash equivalents, and marketable securities totaled $175.8M as of September 30, 2025, down from $212.5M at year-end 2024.
No revenue generated; accumulated deficit of $272.2M as of September 30, 2025.
Outlook and guidance
Cash runway expected to fund operations through 2027, but additional capital will be needed for future development and commercialization.
Initial clinical data for CLYM116 and subcutaneous budoprutug expected in 2026; ITP and SLE trial data anticipated in H2 2026.
Anticipates increased expenses as clinical programs advance and corporate infrastructure expands.
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