)
Enliven Therapeutics (ELVN) investor relations material
Enliven Therapeutics Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Reported positive initial Phase 1b data for ELVN-001 in chronic myeloid leukemia (CML), showing strong efficacy in heavily pretreated patients.
Initiation of Phase 3 ENABLE-2 pivotal trial for ELVN-001 expected in the second half of 2026, with key data readouts and regulatory milestones anticipated throughout 2026.
Leadership transition with Rick Fair appointed CEO in December 2025 and Scott Garland joining the Board in January 2026, aligning governance for late-stage development and commercialization.
Financial highlights
Cash, cash equivalents, and marketable securities totaled $462.6 million as of December 31, 2025, providing runway into the first half of 2029.
R&D expenses were $21.2 million for Q4 2025 (up from $20.7 million in Q4 2024) and $85.9 million for FY 2025 (up from $80.8 million in FY 2024).
G&A expenses rose to $13.0 million for Q4 2025 (from $6.2 million in Q4 2024), mainly due to stock-based compensation related to CEO transition; FY 2025 G&A was $33.8 million (up from $23.8 million in FY 2024).
Net loss was $29.7 million for Q4 2025 (vs. $23.2 million in Q4 2024) and $103.7 million for FY 2025 (vs. $89.0 million in FY 2024).
Outlook and guidance
Additional Phase 1 data from ENABLE trial to be presented mid-2026.
Regulatory alignment with FDA on dose selection and Phase 3 trial design expected in 2026.
ENABLE-2 Phase 3 trial initiation planned for the second half of 2026.
Next Enliven Therapeutics earnings date
Next Enliven Therapeutics earnings date
The essential earnings season companion
The #1 app for qualitative research. Live earnings calls, AI chat, transcripts, and more. All for free.
Live calls and transcripts
Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.
Find what you need faster
Search for any keyword across all transcripts simultaneously.
Easily store key findings
Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Your watchlist. Your dashboard.
Follow the companies that matter to you. Get a personalized feed with real-time updates.
Be the first to know
Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.
Consensus estimates
Access analyst consensus estimates, valuation multiples, and revenue segments splits.
All IR material in one place
The easiest way to stay updated during earnings season.
Global coverage
All events from public companies. Live and recorded.
Just click and listen
No webcast links. No manual registrations.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
I can't remember the last time an app had such a positive impact on my investment process.
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
I can't remember the last time an app had such a positive impact on my investment process.
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
Frequently asked questions
Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.
Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.
Explore our global coverage
)
)