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Investor Relations14 Oct 2025
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Enliven Therapeutics (ELVN) investor relations material
Enliven Therapeutics Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary13 Aug, 2025
Executive summary
Advancing ELVN-001 to a pivotal Phase 3 trial in 2026, with positive Phase 1 data showing a 47% cumulative MMR rate and 32% achieving MMR by 24 weeks in CML; favorable safety and tolerability reported.
Exploring alternatives for ELVN-002, with no plans to develop the HER2 program beyond 2025.
Strengthened balance sheet with a $230M public offering in June 2025 and $90M private placement in March 2024.
Ended Q2 2025 with $490.5M in cash, cash equivalents, and marketable securities.
Accumulated deficit reached $297.4M as of June 30, 2025, with continued operating losses expected.
Financial highlights
Net loss was $25.3M for Q2 2025, compared to $20.0M for Q2 2024; net loss per share was $(0.49) for Q2 2025.
Operating expenses for Q2 2025 were $28.6M, up from $24.6M in Q2 2024, driven by higher R&D and G&A costs.
R&D expenses were $21.5M and G&A expenses were $7.1M for Q2 2025.
Interest and other income declined to $3.2M in Q2 2025 from $4.1M–$4.7M in Q2 2024.
Cash used in operating activities was $41.2M for the first half of 2025.
Outlook and guidance
Cash, cash equivalents, and marketable securities are expected to fund operations and capital requirements into the first half of 2029.
Anticipates increased expenses as ELVN-001 advances to Phase 3 and as the pipeline expands.
No meaningful revenue expected until regulatory approval and commercialization of product candidates.
Assess ELVN-001's competitive edge in CML therapy.
When will the Phase 3 pivotal trial start?
Explain the variance in R&D expenses YOY.
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Next Enliven Therapeutics earnings date
Q3 20257 Nov, 2025
Next Enliven Therapeutics earnings date
Q3 20257 Nov, 2025
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Frequently asked questions
Enliven Therapeutics Inc. is a clinical-stage biopharmaceutical company dedicated to the discovery and development of small molecule kinase inhibitors for cancer treatment. The company aims to address both existing and emerging unmet needs in oncology with a precision approach designed to improve patient survival and overall well-being. Their development pipeline includes advanced candidates such as ELVN-001 and ELVN-002, which are being explored for their potential to offer enhanced selectivity, combinability, and safety in treatment protocols. The company is headquartered in Boulder, Colorado, and its shares are listed on the Nasdaq.
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