Esperion Therapeutics
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Esperion Therapeutics (ESPR) investor relations material

Esperion Therapeutics The Citizens Life Sciences Conference 2026 summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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The Citizens Life Sciences Conference 2026 summary11 Mar, 2026

Financial performance and growth

  • Achieved 38% year-over-year total revenue growth and 34% year-over-year TRx growth, with $408 million in total revenue for the year and 11% TRx growth quarter-over-quarter.

  • Strong commercial access with 90% coverage in both commercial and Medicare segments, and stable gross-to-net projections.

  • International partnerships are driving growth, with significant contributions from Europe (notably Germany, Belgium, UK, and France) and Japan, where sales exceeded expectations.

  • Cash position is strong, ending the year with $168 million and improving, while continuing to deleverage and maintain financial flexibility.

  • Confident in sustaining growth rates, with expectations for continued momentum and no end in sight to current growth trajectory.

Strategic acquisition and integration

  • Acquired Corstasis for $75 million upfront and up to $180 million in milestone payments, plus low double-digit royalties, with deal expected to close in early April.

  • Acquisition brings a unique nasal loop diuretic, Enbumyst, approved in September 2025, targeting heart failure patients resistant to oral diuretics.

  • Integration plans include leveraging existing commercial infrastructure, expanding hospital and acute care coverage, and building payer access.

  • Global rights to the acquired product open options for expansion in Europe, Asia, and other regions.

  • Pre-integration activities underway, with plans to rapidly scale commercialization and awareness post-close.

Commercial strategy and market positioning

  • Focused on maximizing the Bempedoic acid franchise (NEXLIZET, NEXLETOL) and integrating Enbumyst into the portfolio.

  • Key messages to healthcare providers emphasize CLEAR Outcomes data, risk reduction, and unique benefits for statin-intolerant patients.

  • Digital marketing delivers strong ROI, especially in under-covered geographies, and will be further expanded.

  • Ongoing evaluation and expansion of field force to support both existing and new products.

  • Guidelines expected soon are anticipated to provide a significant tailwind for Bempedoic acid products.

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Q1 20265 May, 2026
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Frequently asked questions

Esperion Therapeutics, Inc. is a pharmaceutical company focused on the research, development, and commercialization of therapies to treat cardiovascular and metabolic diseases. The company specializes in developing oral, non-statin medications aimed at lowering cholesterol levels and addressing other factors contributing to cardiovascular risk. The company is headquartered in Ann Arbor, Michigan, and its shares are listed on the NASDAQ.

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