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Investor Relations14 Oct 2025
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Esperion Therapeutics (ESPR) investor relations material
Esperion Therapeutics H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 27th Annual Global Investment Conference summary8 Sep, 2025
Commercial performance and product adoption
Bempedoic acid-based products are approved in 40 countries for lipid lowering and cardiovascular risk reduction, with strong double-digit growth in both the US and Europe.
Second quarter US sales reached $41 million, with total revenue at $87 million, marking one of the best quarters to date.
92% commercial and 75% Medicare coverage achieved, making access easier for prescribers and patients.
European guidelines granted bempedoic acid a class 1a recommendation, and US guidelines are expected to be updated in early 2025.
Expansion into Japan is progressing, with tentative approval and milestone payments expected upon final regulatory and pricing decisions.
Clinical differentiation and competitive landscape
Bempedoic acid is the only oral non-statin lipid-lowering agent studied in statin-intolerant populations, showing significant reductions in fatal and non-fatal MI and revascularization.
Combination therapy is now recommended for lipid lowering, with bempedoic acid highlighted as foundational in new European guidelines.
Competitive products face challenges such as complex dosing or prior failures in the class, while bempedoic acid benefits from robust outcomes data.
Pipeline and R&D initiatives
Lead compound for primary sclerosing cholangitis (PSC) announced, targeting a rare disease affecting 72,000 patients globally, with IND filing planned for next year and potential launch by 2029 or 2030.
Preclinical models show promising results in addressing liver injury and fibrosis, with the candidate having its own IP and global rights.
Additional pipeline programs in kidney disease are under development, leveraging ACLY biology as a platform.
Future uranium contract pricing structure
ISR mining cost structure advantage
Lost Soldier ISR resource applicability
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Next Esperion Therapeutics earnings date
Q3 20256 Nov, 2025
Next Esperion Therapeutics earnings date
Q3 20256 Nov, 2025
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Leroy DaleyApp Store
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Eferix Drawings Google Play
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Frequently asked questions
Esperion Therapeutics, Inc. is a pharmaceutical company focused on the research, development, and commercialization of therapies to treat cardiovascular and metabolic diseases. The company specializes in developing oral, non-statin medications aimed at lowering cholesterol levels and addressing other factors contributing to cardiovascular risk. The company is headquartered in Ann Arbor, Michigan, and its shares are listed on the NASDAQ.
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