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Esperion Therapeutics (ESPR) investor relations material
Esperion Therapeutics Jefferies London Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Jefferies London Healthcare Conference 2025 summary18 Nov, 2025
Recent progress and achievements
Cardiovascular outcomes trial label update in April 2024 expanded the addressable market from 10 million to 70 million patients, driving double-digit quarterly growth and broader payer reimbursement.
Debt has been reduced, with a $55 million stub paid down, and the company will end the year with less debt than it started.
European guidelines granted bempedoic acid a class 1A recommendation, and similar U.S. guideline updates are expected in early 2026.
Market access and payer positioning are strong, with high approval rates and minimal prior authorization barriers.
Anticipated guideline updates and market impact
U.S. guidelines are expected to align closely with recent European recommendations, likely published in early 2026.
Updated guidelines are anticipated to boost awareness and further unlock market potential, especially among primary care physicians.
Access is largely secured, with execution and market penetration being the focus for 2026.
Commercial strategy and salesforce expansion
Shift in prescriber mix toward primary care (now 60% PCPs, 40% cardiologists) due to broader label and statin intolerance inclusion.
Current salesforce includes 155 reps and 5 key account managers, covering 70% of the target market in-person and 90% with digital outreach.
Plans to expand the salesforce by 30-40 reps to increase promotional sensitivity and market coverage, with manageable incremental OpEx.
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Next Esperion Therapeutics earnings date
Piper Sandler 37th Annual Healthcare Conference3 Dec, 2025
Next Esperion Therapeutics earnings date
Piper Sandler 37th Annual Healthcare Conference3 Dec, 2025
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Frequently asked questions
Esperion Therapeutics, Inc. is a pharmaceutical company focused on the research, development, and commercialization of therapies to treat cardiovascular and metabolic diseases. The company specializes in developing oral, non-statin medications aimed at lowering cholesterol levels and addressing other factors contributing to cardiovascular risk. The company is headquartered in Ann Arbor, Michigan, and its shares are listed on the NASDAQ.
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