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Esperion Therapeutics (ESPR) investor relations material
Esperion Therapeutics Piper Sandler 37th Annual Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Piper Sandler 37th Annual Healthcare Conference summary3 Dec, 2025
Key catalysts and recent progress
Label expansion in April 2024 increased total addressable market from 10 million to 70 million, enabling broader promotion and use with or without statins.
Strong momentum observed in Q3 and Q4, with early signs of future growth from recent initiatives.
Capital structure improvements and outcome study results have positioned the company for double-digit growth.
Clinical guidelines and market influence
Bempedoic acid received a Class I-A recommendation in updated European guidelines for statin-intolerant patients.
Guidelines highlight bempedoic acid as foundational therapy, with combinations achieving over 70% LDL reduction.
U.S. guidelines expected in early 2025, likely to align closely with European recommendations, providing significant tailwinds through 2026.
Guidelines are highly influential among cardiologists and primary care physicians, shaping prescribing behavior.
Product positioning and differentiation
Statin intolerance is broadly defined, encompassing over 20 million patients, and is a key focus for positioning.
Bempedoic acid offers unique benefits: outcome study data, hs-CRP lowering, and primary prevention claims with 39% reduction.
Oral administration preferred by patients over injectables, with better efficacy in primary prevention compared to competitors.
How will US guidelines translate to physician adoption?
Basis for exclusivity beyond 2031 patent?
How does food effect impact oral PCSK9 competition?
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Next Esperion Therapeutics earnings date
Q4 20253 Mar, 2026
Next Esperion Therapeutics earnings date
Q4 20253 Mar, 2026
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Frequently asked questions
Esperion Therapeutics, Inc. is a pharmaceutical company focused on the research, development, and commercialization of therapies to treat cardiovascular and metabolic diseases. The company specializes in developing oral, non-statin medications aimed at lowering cholesterol levels and addressing other factors contributing to cardiovascular risk. The company is headquartered in Ann Arbor, Michigan, and its shares are listed on the NASDAQ.
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