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Evaxion Biotech A/S (EVAX) investor relations material

Evaxion Biotech A/S Corporate Presentation summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Corporate Presentation summary15 Oct, 2025

Strategic vision and platform

  • Focuses on AI-powered development of novel vaccines for cancer and infectious diseases, leveraging a clinically validated AI-Immunology™ platform for rapid and accurate target discovery and design.

  • Maintains a multidisciplinary capability set with advanced wetlab and animal facilities, supporting both preclinical and clinical programs.

  • Pursues a multi-partner approach, enabling value creation through partnerships and out-licensing, including transformative deals with major pharmaceutical companies.

  • Strategic ambition centers on becoming the AI partner of choice, generating positive cash flow, and driving best-in-class target discovery and validation.

Financial highlights and partnerships

  • Secured a $7.5 million exercise fee from MSD for the EVX-B3 program, extending cash runway to H1 2027 and potential future payments up to $592 million.

  • MSD partnership validates the AI-Immunology™ platform and pipeline, with MSD assuming all future development costs for EVX-B3.

  • MSD is the largest shareholder, holding close to 20% equity stake.

  • As of June 30, 2025, cash position was $14.7 million, with a market capitalization of $29.3 million.

Pipeline and clinical progress

  • Broad pipeline includes candidates for advanced melanoma (EVX-01, EVX-02, EVX-03), S. aureus (EVX-B1), N. gonorrhoeae (EVX-B2), Group A Streptococcus (EVX-B4), and Cytomegalovirus (EVX-V1).

  • EVX-01 achieved a 69% overall response rate in phase 2 for advanced melanoma, with 80% of vaccine targets inducing specific immune responses.

  • EVX-02 showed 100% relapse-free survival and T-cell response in adjuvant melanoma patients.

  • EVX-03 combines personalized neoantigens and ERV antigens, showing complete responses in mouse models and is ready for regulatory submission.

  • Infectious disease candidates demonstrate strong preclinical efficacy and address significant unmet needs, including antibiotic resistance.

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Frequently asked questions

Evaxion Biotech utilizes the AI platform, which is designed to reduce the identification of novel epitopes, and to develop neoantigens, vaccines, and antibody-based therapies; pNLS platform that is designed to identify novel protein structures through computational design; and 2D-to-3D structural similarity searching algorithm. It is developing EB023, a peptide based immunotherapy for the treatment of head and neck cancer. Evaxion Biotech A/S was founded in 2008 and is headquartered in Copenhagen, Denmark.

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