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EXACT Therapeutics (EXTX) investor relations material
EXACT Therapeutics H2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Achieved significant progress in advancing PS101 for locally advanced pancreatic cancer, with ENACT Phase 2 trial initiated and first patient treated in June 2025.
Positive final results from ACTIVATE Phase 1 trial in liver metastases, showing 4x greater tumor shrinkage with PS101 plus chemotherapy.
Strengthened strategic partnership with GE HealthCare and secured additional patents.
Maintained a focused strategy on high unmet medical need cancers, especially pancreatic cancer.
Financial highlights
Total operating costs for 2025 were NOK 84.9 million, up from NOK 52.9 million in 2024, reflecting increased R&D activity.
Comprehensive loss for 2025 was NOK -87.0 million, compared to NOK -52.3 million in 2024.
Cash and cash equivalents at year-end 2025 were NOK 24.3 million, down from NOK 100 million at end of 2024.
Equity ratio declined to 46% (from 75% in 2024) due to increased expenses and reduced cash position.
Government grants recognized totaled NOK 7.8 million in 2025.
Outlook and guidance
Focus in 2026 will be on executing the ENACT Phase 2 trial, with interim analysis and patient recruitment completion expected in H2 2026.
Strategic partnership with GE HealthCare to continue, aiming for a commercial-ready ultrasound platform.
Preclinical programs in blood-brain barrier, immuno-oncology, and gene therapy to progress.
Successful warrant exercise in early 2026 raised NOK 59 million, ensuring liquidity for planned activities through 2026 and beyond.
- Strong early clinical results and secured funding support expansion in oncology and beyond.EXTX
Investor update11 Feb 2026 - $13M raised, including $7M from a medtech leader, to fund phase II trial and expand ACT platform.EXTX
Status update6 Feb 2026 - Ultrasound-activated therapy achieved >10x tumor reduction and advances to Phase 2 in pancreatic cancer.EXTX
ISTU 2024 presentation6 Feb 2026 - ACT delivers >10x tumor shrinkage in liver metastases and advances to Phase 2 pancreatic cancer trials.EXTX
CMR Symposium 2024 presentation6 Feb 2026 - PS101 delivers promising early results in pancreatic cancer, with strong clinical and financial momentum.EXTX
Company presentation6 Feb 2026 - ACT technology shows strong clinical promise in oncology, with Phase 2 trials underway.EXTX
DNB Carnegie Nordic Healthcare Conference Presentation25 Nov 2025 - ENACT Phase 2 trial launched, ACTIVATE Phase 1 results strong, cash burn rises with clinical progress.EXTX
H1 202525 Sep 2025 - Net loss widened as EXACT pivots to pancreatic cancer trials and seeks urgent new funding.EXTX
H1 202413 Jun 2025 - NOK 145 million raised and GE HealthCare partnership drive EXACT's 2025 clinical focus.EXTX
H2 20249 Jun 2025
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