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Exagen (XGN) investor relations material

Exagen Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary4 Nov, 2025

Executive summary

  • Achieved record Q3 2025 revenue of $17.2 million, a 38% year-over-year increase, driven by higher test volume and ASP expansion, with AVISE CTD test volume up 16%.

  • Gross margin improved to 58.4% in Q3 2025 from 55.8% in Q3 2024, reflecting operational efficiencies and new biomarker launches.

  • Net loss for Q3 2025 was $7.1 million, primarily due to higher interest expense and warrant liability revaluation.

  • Successfully launched new anti-PAD4 antibody assays and seronegative RA markers, further differentiating the rheumatoid arthritis portfolio.

  • Cash and cash equivalents stood at $35.7 million as of September 30, 2025.

Financial highlights

  • Q3 2025 revenue reached $17.2 million, a record high and nearly 38% increase year-over-year; nine-month revenue was $49.9 million.

  • Gross margin for Q3 2025 was 58.4%; year-to-date gross margin was just over 59%.

  • Operating expenses for Q3 2025 were $13.2 million, up 13.2% year-over-year, mainly due to R&D and sales expansion.

  • Adjusted EBITDA loss improved to $1.9 million in Q3 2025 from $4 million in Q3 2024.

  • Net loss per share for Q3 2025 was $(0.31); cash used in operations for nine months was $10.6 million.

Outlook and guidance

  • Reiterated 2025 full-year revenue guidance of $65–$70 million, with positive adjusted EBITDA expected in Q4 if revenue reaches the high end.

  • Revenue growth guidance for 2025 remains 17% to over 25%.

  • Existing cash and anticipated revenue are expected to fund operations for at least the next 12 months.

  • Long-term ASP target remains $500–$600, with $500 expected to drive cash flow positivity.

  • Management expects moderate increases in operating expenses to support growth, but these will decrease as a percentage of revenue.

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Frequently asked questions

Exagen Inc. is a life sciences company focused on transforming the diagnosis, prognosis, and management of autoimmune diseases. The company develops and commercializes advanced diagnostic solutions designed to provide actionable insights for physicians treating conditions such as lupus and rheumatoid arthritis. Exagen’s product portfolio includes proprietary tests and services that integrate genomic and proteomic technologies to support personalized patient care. The company is headquartered in Vista, California, and its shares are listed on the NASDAQ.

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