ExpreS2ion Biotech
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ExpreS2ion Biotech (EXPRS2) investor relations material

ExpreS2ion Biotech Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary12 Nov, 2026

Executive summary

  • ES2B-C001 enrolled 19 patients; 12 of 13 evaluable patients had at least a twofold anti-HER2 antibody increase, with no dose-limiting toxicities reported.

  • The Phase I primary readout is expected in Q1 2027; Phase II is targeted for H2 2027, subject to partnering and financing.

  • Q3 net loss was SEK 9.935m; cash was SEK 23.963m at 30 September, before SEK 19.3m in post-period gross financing proceeds.

Financial highlights

  • Q3 operating income was SEK 2.292m, flat YoY; net sales rose 286% to SEK 1.364m while other operating income fell 52% to SEK 0.928m.

  • Q3 operating costs rose 25% to SEK 15.052m; operating loss was SEK 12.760m versus SEK 9.746m, and net loss was SEK 9.935m versus SEK 8.445m.

  • 9M net sales rose 37% to SEK 4.413m; operating income was SEK 20.707m versus SEK 8.674m.

  • 9M operating costs were SEK 57.4m versus SEK 42.8m; 9M net loss narrowed 2% to SEK 29.226m from SEK 29.910m.

  • Q3 R&D spend was SEK 3.7m, up 56% YoY, reflecting ES2B-C001 trial and higher CMC costs.

Outlook and guidance

  • ES2B-C001 priming is expected to finish in Q4 2026; translational results are expected by year-end, database lock in February 2027 and primary readout in Q1 2027.

  • Proposed Phase II scope is 80–120 first-line HER2-positive metastatic breast cancer patients, with 24-month PFS as the readout; H2 2027 start depends on partner and funding.

  • Nipah toxicology and IND-enabling work is planned for 2027, with Phase I initiation thereafter, subject to clinical, regulatory, manufacturing, funding and partner factors.

  • VAC-087 and VAC-093 malaria trials are expected to complete in Q4 2026; BIO-005 completion is expected in Q2 2027.

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Frequently asked questions

ExpreS2ion Biotech Holding AB (publ), through its subsidiary, ExpreS2 ion Biotechnologies ApS, develops, produces, and delivers therapeutics or diagnostic proteins in Denmark and internationally. The company uses its expression system technology to offer services that include cell line development, screening of cell bank clones developed in the clients' host cell line of interest, analytical services comprising host cell line development, clone screening and base media optimization, process scale-up and GMP manufacturing. It also manufactures and distributes therapeutic proteins based on prokaryotic and eukaryotic expression systems using the GalXC protein expression system to EU/US chemical and health companies.