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ExpreS2ion Biotech (EXPRS2) investor relations material
ExpreS2ion Biotech Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
ES2B-C001 enrolled 19 patients; 12 of 13 evaluable patients had at least a twofold anti-HER2 antibody increase, with no dose-limiting toxicities reported.
The Phase I primary readout is expected in Q1 2027; Phase II is targeted for H2 2027, subject to partnering and financing.
Q3 net loss was SEK 9.935m; cash was SEK 23.963m at 30 September, before SEK 19.3m in post-period gross financing proceeds.
Financial highlights
Q3 operating income was SEK 2.292m, flat YoY; net sales rose 286% to SEK 1.364m while other operating income fell 52% to SEK 0.928m.
Q3 operating costs rose 25% to SEK 15.052m; operating loss was SEK 12.760m versus SEK 9.746m, and net loss was SEK 9.935m versus SEK 8.445m.
9M net sales rose 37% to SEK 4.413m; operating income was SEK 20.707m versus SEK 8.674m.
9M operating costs were SEK 57.4m versus SEK 42.8m; 9M net loss narrowed 2% to SEK 29.226m from SEK 29.910m.
Q3 R&D spend was SEK 3.7m, up 56% YoY, reflecting ES2B-C001 trial and higher CMC costs.
Outlook and guidance
ES2B-C001 priming is expected to finish in Q4 2026; translational results are expected by year-end, database lock in February 2027 and primary readout in Q1 2027.
Proposed Phase II scope is 80–120 first-line HER2-positive metastatic breast cancer patients, with 24-month PFS as the readout; H2 2027 start depends on partner and funding.
Nipah toxicology and IND-enabling work is planned for 2027, with Phase I initiation thereafter, subject to clinical, regulatory, manufacturing, funding and partner factors.
VAC-087 and VAC-093 malaria trials are expected to complete in Q4 2026; BIO-005 completion is expected in Q2 2027.
- Phase I antibody responses underpin a planned ES2B-C001 Phase II start in H2 2027.EXPRS2
26th Annual Biotech in Europe Forum - HER2+ breast cancer vaccine nears clinical trial as SEK 60M rights issue supports 2026 data goal.EXPRS2
H C Andersen Capital Life Science Seminar - Lead HER2-targeting vaccine nears clinical trials, backed by strong data and major partnerships.EXPRS2
Stora Aktiedagarna Stockholm - Advancing a first-in-class HER2 vaccine for breast cancer with strong preclinical and early clinical progress.EXPRS2
H.C. Andersen Capital Institutional Seminar presentation - First-in-class HER2 immunotherapy advances in trials, with major milestones expected by 2026.EXPRS2
Aktiespararna Aktiedagen - Promising HER2 vaccine shows durable immune response and clear path to Phase II.EXPRS2
Sachs European Life Science Forum - First-in-class HER2 immunotherapy shows promise in early trials, with major catalysts ahead.EXPRS2
Økonomisk Ugebrev Life Science Investor Conference - ES2B-C001 nears phase I, showing strong efficacy, safety, and commercial promise for HER2+ breast cancer.EXPRS2
BioStock Life Science - HER2-targeted VLP vaccine with strong preclinical results enters phase I trials in 2025.EXPRS2
Biostock Life Science Summit
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Next ExpreS2ion Biotech earnings date
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