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Genfit (GNFT) investor relations material

Genfit Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary22 Sep, 2025

Executive summary

  • Cash and cash equivalents reached €107.5 million as of June 30, 2025, excluding a €26.5 million milestone received in July 2025 for Iqirvo® pricing and reimbursement in three major European countries.

  • Revenues for 1H25 were €35.7 million, down from €61.2 million in 1H24, mainly from milestone and royalty payments related to Iqirvo®.

  • Net loss for 1H25 was €10.0 million, compared to a net profit of €30.3 million in 1H24, driven by higher R&D expenses and financial charges.

  • Discontinuation of the VS-01 program in ACLF is expected to reduce operating expenses and extend the cash runway beyond 2028.

  • Strong sales trajectory for Iqirvo® in PBC reported by Ipsen, with positive market dynamics following a competitor's US exit.

Financial highlights

  • Cash and cash equivalents increased to €107.5 million from €81.8 million at year-end 2024.

  • Revenues and other income totaled €35.7 million in 1H25, primarily from a €26.5 million milestone and €6.9 million in royalties.

  • Operating expenses rose to €35.6 million in 1H25, up from €30.0 million in 1H24, mainly due to increased R&D spending.

  • Financial loss of €10.2 million in 1H25, mainly due to debt issuance costs and royalty financing charges.

  • Net loss of €10.0 million in 1H25, compared to net profit of €30.3 million in 1H24.

Outlook and guidance

  • Cash runway projected to extend beyond 2028, supported by milestone revenues, royalty financing, and reduced expenses after VS-01 discontinuation.

  • Phase 1b data for GNS561 in CCA and safety/efficacy data for G1090N in ACLF expected by end of 2025.

  • Multiple ACLF pipeline assets advancing, with key clinical milestones anticipated through 2026 and 2027.

  • Market withdrawal of a key competitor in the US expected to benefit Iqirvo® sales.

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Frequently asked questions

Genfit S.A. is a biopharmaceutical company focused on discovering and developing innovative therapeutic and diagnostic solutions in the areas of liver-related diseases and metabolic disorders. The company specializes in creating proprietary drug candidates and biomarkers to address unmet medical needs, particularly in non-alcoholic steatohepatitis (NASH) and other chronic liver conditions. Genfit's portfolio includes both therapeutic and diagnostic assets aimed at improving patient outcomes through targeted treatment strategies and precision medicine. The company is headquartered in Loos, France, and its shares are listed on the Euronext Paris.

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