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Company Research29 Mar 2024
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Gilead Sciences (GILD) investor relations material
Gilead Sciences Evercore ISI 8th Annual HealthCONx Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Evercore ISI 8th Annual HealthCONx Conference summary3 Dec, 2025
R&D strategy and portfolio updates
Focus remains on virology, oncology, and inflammation, with strong performance and multiple launches in the past year.
HIV prevention and treatment portfolio is expanding, with new long-acting injectable and oral regimens under development.
Portfolio prioritization led to advancement of GS-3242, a long-acting integrase inhibitor, over similar candidates.
Ongoing studies include Purpose 365 for annual HIV prevention and Artistry trials for new HIV regimens.
Inflammation pipeline includes oral alpha-4 beta-7 in phase II for IBD, with potential for combination therapies.
HIV pipeline and clinical trial insights
Intramuscular HIV prevention options are being studied for both annual and six-month dosing, with decisions pending data.
High patient retention and compliance observed in clinical trials for long-acting injectables, with minimal issues from injection site nodules.
GS-3242 is prioritized for long-acting treatment, while Biktarvy remains standard of care for naive patients.
Combination regimens are being developed to address resistance, with encouraging data on low resistance formation.
BIC-Len regimen is positioned for switch settings, with ongoing studies in both complex and general switch populations.
Inflammation and metabolic pipeline
Oral GLP-1 candidate is in phase I, with future development or partnership decisions pending data.
Oral alpha-4 beta-7 for IBD is a strategic focus, with phase II data expected soon and potential for use in various disease stages.
Internal combination partners for IBD include TPL2 and FXR agonists, with external partnerships also considered.
RA pipeline includes a PD-1 agonist in clinical trials.
BIC/LEN's role in HIV treatment strategy
Oral GLP-1 & alpha-4-beta-7: Strategic fit?
How is Gilead positioned for in vivo CAR T?
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Next Gilead Sciences earnings date
Q4 202510 Feb, 2026
Next Gilead Sciences earnings date
Q4 202510 Feb, 2026
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Frequently asked questions
Gilead Sciences, Inc. discovers, develops, and commercializes medicines in the areas of unmet medical need in the United States, Europe, and internationally. The company's products address chronic diseases such as hepatitis C virus infection; and the company participates in the product development partnerships with Bristol-Myers Squibb Company to develop HIV direct acting antiviral drugs based on discoveries made at the company's San Francisco research facility. The company was founded in 1987 and is headquartered in Foster City, California.
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