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Gilead Sciences Q2 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2026 earnings summary4 Aug, 2026

Executive summary

  • Q2 2026 base business sales grew 10% year-over-year, marking the strongest Q2 growth in three years, driven by HIV, Trodelvy, and Livdelzi, while Veklury and Cell Therapy sales declined.

  • HIV sales rose 12% year-over-year to $5.7 billion, with PrEP sales doubling to over $1 billion quarterly for the first time, led by Biktarvy, Descovy, and Yeztugo.

  • Trodelvy sales increased 26% year-over-year to $457 million, with new first-line metastatic TNBC approvals and expanded clinical programs.

  • Liver disease business delivered over 100% growth in Livdelzi sales and launched Hepcludex for HDV in the U.S.

  • Multiple product launches and positive clinical milestones achieved, including three FDA approvals and three positive Phase 3 updates.

Financial highlights

  • Total Q2 2026 product sales (excluding Veklury) reached $7.6 billion, up 10% year-over-year; including Veklury, sales were up 8% to $7.6 billion.

  • HIV sales reached $5.7 billion, up 12% year-over-year and 13% sequentially; Biktarvy sales were $3.8 billion, Descovy $967 million.

  • Trodelvy sales were $457 million (up 26% year-over-year); Livdelzi sales were $167 million (more than doubled year-over-year).

  • Cell therapy sales were $417 million, down 14% year-over-year but up 2% sequentially.

  • Non-GAAP diluted EPS was $(6.75) due to $11.2 billion in acquired IPR&D expenses; excluding these, EPS was $2.27, up 13% year-over-year.

Outlook and guidance

  • Full-year 2026 product sales expected between $30.1–$30.4 billion; excluding Veklury, $29.8–$30.1 billion (6%-7% growth year-over-year).

  • Full-year HIV sales expected to grow 9%-10%, with Yeztugo targeting $1 billion in sales.

  • Cell therapy sales expected to decline mid-teens percent year-over-year.

  • Full-year non-GAAP EPS (excluding IPR&D and non-recurring items) raised to $8.45–$8.85.

  • Veklury full-year sales guidance reduced to ~$300 million.

Drivers of the $11.1 billion IPR&D charge
Competitive headwinds in the Cell Therapy unit
Clinical data leading to EVOKE-03 termination
Impact of ACA subsidy changes on HIV market
Anito-cel launch readiness and PDUFA outlook
Yeztugo persistency vs oral PrEP competition
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