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Ginkgo Bioworks (DNA) investor relations material

Ginkgo Bioworks Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary6 Nov, 2025

Executive summary

  • Focused on expanding autonomous lab robotics, AI-driven tools, and software for bioscience customers, with strategic partnerships extended, including Bayer and BARDA, and a shift toward a tools business model.

  • Revenue declined significantly year-over-year, mainly due to lower non-cash revenue from contract terminations and reduced activity in both Cell Engineering and Biosecurity segments.

  • Restructuring actions, including workforce reductions and facility consolidations, were largely completed, driving cost reductions and improved operational efficiency.

  • Maintained a strong liquidity position with $462 million in cash, cash equivalents, and marketable securities as of September 30, 2025, and no bank debt.

  • Strategic partnerships and government contracts, such as the $22 million BARDA award and Bayer extension, support growth in AI-driven bioscience and automation.

Financial highlights

  • Q3 2025 total revenue was $39 million, down 56% year-over-year, mainly due to a prior year non-cash deferred revenue release; Cell Engineering revenue was $29 million, Biosecurity revenue was $9–10 million.

  • Net loss (GAAP) for Q3 2025 was $81 million, compared to $56 million in Q3 2024; adjusted EBITDA for Q3 2025 was $(56) million, compared to $(20) million in Q3 2024.

  • Cash burn in Q3 2025 was $28 million, a significant reduction from prior periods.

  • Operating expenses for Q3 2025 were $129 million, down from $144 million in Q3 2024.

  • Cash used in operations for the first nine months of 2025 was $123 million, a substantial improvement from the prior year.

Outlook and guidance

  • Full-year 2025 total revenue guidance reaffirmed at $167–$187 million, with Cell Engineering expected at $117–$137 million and Biosecurity at least $40 million.

  • Management expects expenditures to exceed revenue over the next 12 months as investments continue in R&D, platform expansion, and restructuring.

  • Continued focus on cost reduction and cash burn improvements while investing in AI and automation for growth.

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Frequently asked questions

Ginkgo Bioworks Holdings, Inc, a biomolecular engineering company, develops biological manufacturing technologies to program cells for molecular manufacturing systems. Ginkgo Bioworks Holdings software engineering platform uses the widely used programming language Python and its library of bioinformatics functions and statistical methods. Ginkgo Bioworks' programs are designed to modify bacterial genes to make organic compounds such as vanillin, scents to produce civetone in bacteria, Beta-carotene and lycopene in yeast cells, gluconic acid in E. coli; and shikimic acid and artemisinic acid in yeast cells. The company sells its products to pharmaceutical companies including AstraZeneca Group and Eli Lilly & Co; chemical companies including Firmenich SA; flavor, aroma, and fragrance companies; craft breweries; and others.

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