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Glaukos (GKOS) investor relations material
Glaukos 44th Annual J.P. Morgan Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Business innovation and product development
Focus on innovation has led to leadership in MIGS and creation of new markets in ophthalmology, including procedural pharmaceuticals and corneal cross-linking.
Over $800 million invested in R&D since 2018, resulting in 12 commercial products and 13 in development.
Platforms like iStent, iDose, iLink, and iLution drive cascades of new products and address unmet clinical needs.
Sustained over 20% CAGR for 10 years, with a record quarter and 30% market growth recently.
Expansion into rare diseases and transdermal therapies, with plans to build a retinal company.
Glaucoma treatment paradigm and product pipeline
Current glaucoma treatment is seen as outdated; focus is on interventional approaches for better adherence and outcomes.
iDose TR offers sustained intraocular pressure reduction, with 81% of patients off all medications at one year and 70% well controlled at three years.
New products like iDose Trio and iDose TREX aim to extend duration and facilitate in-office use, with clinical trials underway.
iStent infinite demonstrated superior safety and efficacy in trials, with plans to expand indications by 2027.
Market opportunity includes 12 million diagnosed eyes, with potential for multiple interventions per patient over 20 years.
Commercial strategy and market expansion
Combination therapy (iDose with iStent) is being studied for additive effects.
In-office injectable therapy and repeat administration approvals are expected to drive adoption.
Vision for 2035 includes as many interventional glaucoma procedures as cataract surgeries.
Full product portfolio covers all stages of glaucoma, aiming for best benefit-to-risk ratio.
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