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GRAIL (GRAL) investor relations material

GRAIL Bernstein Insights: Healthcare Leaders and Disruptors - 2nd Annual Healthcare Forum summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Bernstein Insights: Healthcare Leaders and Disruptors - 2nd Annual Healthcare Forum summary24 Sep, 2025

Market momentum and growth drivers

  • Achieved 22% revenue growth and 30% utilization growth in the first half of 2025, with strong momentum across clinic, self-pay, and employer channels.

  • Employer and life insurance channels are seeing increased interest due to a broader healthcare shift toward wellness and proactive care.

  • Partnerships, such as with Quest Diagnostics, are streamlining physician access and prescription processes.

Reimbursement and legislative landscape

  • The Medicare Multi-Cancer Early Detection (MCED) Act is the most supported healthcare bill in Congress, aiming to enable Medicare coverage for FDA-approved MCED tests.

  • Recent committee hearings have shown strong bipartisan momentum, with optimism for passage if attached to a suitable legislative vehicle.

  • Political factors and legislative packaging remain key variables for the bill's progress.

Competitive positioning and clinical evidence

  • Galleri is the only MCED test fully validated in intended-use populations, with unmatched clinical data and a very low false positive rate (0.5%).

  • Competitors' tests have higher false positive rates, leading to lower positive predictive values and greater clinical burden.

  • Galleri more than doubled cancer detection rates in trials, with half of detected cancers at early stages.

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Frequently asked questions

GRAIL, Inc. is a biotechnology company specializing in the development of advanced technologies for early cancer detection. The company's primary product is the Galleri test, a multi-cancer early detection test designed to screen for a wide range of cancers, particularly those without current recommended screenings. In addition to Galleri, GRAIL is also working on diagnostic aids and minimal residual disease tests to assist in the detection and monitoring of cancer. The company is headquartered in Menlo Park, California, and its shares are listed on the Nasdaq.

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