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GRI Bio (GRI) investor relations material
GRI Bio Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Clinical-stage biopharma focused on therapies for inflammatory, fibrotic, and autoimmune diseases, with lead candidate GRI-0621 targeting idiopathic pulmonary fibrosis (IPF).
GRI-0621 met primary and secondary endpoints in a Phase 2a IPF trial, showing safety, tolerability, and biomarker improvements.
GRI-0803, targeting lupus and other autoimmune disorders, is advancing toward IND-enabling studies and a Phase 1 trial in 2026.
Company remains pre-revenue, with ongoing net losses and a focus on advancing clinical programs and securing additional capital.
Financial highlights
Net loss for 2025 was $12.0 million, compared to $8.2 million in 2024.
Research and development expenses increased to $6.8 million in 2025 from $3.8 million in 2024, mainly due to GRI-0621 clinical development.
General and administrative expenses rose to $5.2 million in 2025 from $4.5 million in 2024.
Cash and cash equivalents as of December 31, 2025, were $8.2 million.
Accumulated deficit reached $51.7 million at year-end 2025.
Outlook and guidance
Existing cash is expected to fund operations into Q1 2027, but only covers preliminary work for a Phase 2b GRI-0621 trial.
Substantial additional capital is required to complete a Phase 2b trial and continue development programs.
Plans to raise further funds through equity, debt, or strategic partnerships.
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