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Investor Relations14 Oct 2025
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GT Biopharma (GTBP) investor relations material
GT Biopharma H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 27th Annual Global Investment Conference summary5 Sep, 2025
Key technology and pipeline updates
Developing trispecific killer cell engager camelid nanobodies for cancer and HIV, with a platform adaptable to multiple targets.
Currently conducting a Phase 1 trial for blood cancer, specifically acute myeloid leukemia, and planning to file an IND for solid tumors by year-end.
Pipeline includes over six candidates, with a focus on expanding into the larger solid tumor oncology market.
Scientific advancements and clinical data
TriKE® molecules combine anti-CD16, IL-15, and tumor antigen targeting, enhancing NK cell activation and proliferation.
First-generation TriKE® (GTB-3550) showed proof of concept with NK cell expansion and blast reduction in AML patients.
Second-generation camelid TriKE® (GTB-3650) demonstrates increased potency and sustained immune activation, with no dose-limiting toxicity observed so far.
Solid tumor and future development plans
B7H3 identified as a promising pan-tumor antigen; proprietary camelid TriKE® shows strong preclinical efficacy in eradicating solid tumor masses.
Planned basket trial for solid tumors will use subcutaneous outpatient therapy, aiming for FDA submission in the coming months.
Seven cohorts will be included to identify responsive tumor types and define the regulatory path over the next few years.
GTB-3650 dose escalation strategy?
Solid tumor trial design impact on market?
CD19 TriKE's autoimmune disease strategy?
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Next GT Biopharma earnings date
Q3 202513 Nov, 2025
Next GT Biopharma earnings date
Q3 202513 Nov, 2025
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Eferix Drawings Google Play
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Frequently asked questions
GT Biopharma Inc. is a biotechnology company focused on developing immuno-oncology therapies for cancer treatment. The company specializes in TriKE (Tri-specific Killer Engager) technology, which is designed to enhance the ability of natural killer (NK) cells to target and destroy cancer cells. GT Biopharma’s pipeline includes investigational treatments for hematologic malignancies and solid tumors. The company is headquartered in Brisbane, California, and its shares are listed on the NASDAQ.
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