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GT Biopharma
GT Biopharma (GTBP) investor relations material
GT Biopharma Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q4 2025 earnings summary2 Mar, 2026
Executive summary
Advanced two TriKE® candidates: GTB-3650 in Phase 1 for hematologic malignancies and GTB-5550 set to begin Phase 1 for B7H3-positive solid tumors in mid-2026.
GTB-3650 Phase 1 trial continues enrolling, with next update expected in Q3 2026 after Cohort 5 completion.
GTB-5550 Phase 1 basket trial will test up to 6 dose levels, followed by Phase 2 expansion in up to seven metastatic disease cohorts.
Financial highlights
Cash and cash equivalents were approximately $7 million as of December 31, 2025, and $9 million as of January 31, 2026, expected to fund operations through Q4 2026.
R&D expenses for 2025 were $3.5 million, down from $5.8 million in 2024, mainly due to reduced production and material costs.
SG&A expenses (excluding stock compensation) were $8.5 million in 2025, relatively flat year-over-year.
Loss from operations was $12.4 million in 2025, compared to $14.4 million in 2024.
Net loss for 2025 was $28.4 million, up from $13.2 million in 2024, primarily due to a non-cash expense from the change in fair value of investment rights tied to Series L Preferred Stock.
Outlook and guidance
Sufficient cash runway is anticipated through Q4 2026.
Next clinical update for GTB-3650 expected in Q3 2026; GTB-5550 Phase 1 trial initiation on track for mid-2026.
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Next GT Biopharma earnings date
Q1 202615 May, 2026
GT Biopharma
Next GT Biopharma earnings date
Q1 202615 May, 2026
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Frequently asked questions
GT Biopharma Inc. is a biotechnology company focused on developing immuno-oncology therapies for cancer treatment. The company specializes in TriKE (Tri-specific Killer Engager) technology, which is designed to enhance the ability of natural killer (NK) cells to target and destroy cancer cells. GT Biopharma’s pipeline includes investigational treatments for hematologic malignancies and solid tumors. The company is headquartered in Brisbane, California, and its shares are listed on the NASDAQ.
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