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Guard Therapeutics Intl (GUARD) investor relations material
Guard Therapeutics Intl Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary13 Nov, 2025
Executive summary
Focus during Q3 2025 was on completing the pivotal phase 2b POINTER study for RMC-035 in open heart surgery; however, negative topline results were reported after the period, prompting a strategic review of future direction.
Despite strong operational execution and external interest, the primary and key secondary endpoints in POINTER were not met, overshadowing earlier promising results from the AKITA phase 2a study.
All development activities have been paused to preserve shareholder value while strategic alternatives, including the GTX platform for chronic kidney disease, are evaluated.
Financial highlights
Net sales were 0 KSEK for both Q3 and the nine-month period (unchanged year-over-year).
Net loss for Q3 was -26,085 KSEK (improved from -31,727 KSEK YoY); for January–September, net loss was -92,522 KSEK (widened from -70,108 KSEK YoY).
Earnings per share for Q3: -1.29 SEK (vs. -2.65 SEK YoY); for nine months: -5.34 SEK (vs. -6.51 SEK YoY).
R&D expenses for Q3: -23,150 KSEK (vs. -29,718 KSEK YoY); for nine months: -83,493 KSEK (vs. -66,001 KSEK YoY), mainly due to the POINTER study.
Cash and cash equivalents at period end: 69,757 KSEK (vs. 66,775 KSEK YoY).
Equity ratio at period end: 78% (vs. 84% YoY).
Outlook and guidance
Strategic review underway following negative POINTER results; all development paused pending outcome.
Available cash is expected to be sufficient to fund operations through 2026.
RMC-035's future in sepsis?
GTX platform's role in new strategy?
Cash runway beyond 2026?
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Next Guard Therapeutics Intl earnings date
Q4 202520 Feb, 2026
Next Guard Therapeutics Intl earnings date
Q4 202520 Feb, 2026
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Frequently asked questions
Guard Therapeutics International AB is a Swedish biopharmaceutical company focused on the development of therapies for the diagnosis and treatment of acute kidney injuries. The company is most known for its investigational drug, ROSGard, a biological candidate designed to prevent kidney damage by mimicking the body's defense system against oxidative stress, thereby protecting, cleaning, and repairing exposed cells and tissues. Guard Therapeutics is headquartered in Stockholm, Sweden, and its shares are listed on the Nasdaq First North.
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