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Heidelberg Pharma (HPHA) investor relations material

Heidelberg Pharma Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary9 Oct, 2025

Executive summary

  • Lead ADC candidate HDP-101 advanced to ninth cohort in Phase I/IIa trial, showing strong safety and efficacy signals in relapsed/refractory multiple myeloma patients.

  • Strategic refocus on HDP-101 due to delayed milestone payment; 75% workforce reduction and pausing of other programs.

  • New clinical data for HDP-101 presented at IMS Annual Meeting, with several patients achieving partial or very good partial responses.

Financial highlights

  • Sales revenue for 9M 2025 was EUR 1.4 million, down from EUR 5.2 million year-over-year.

  • Other income rose to EUR 5.0 million (prior year: EUR 2.4 million), mainly from exchange rate gains.

  • Operating expenses increased to EUR 28.2 million (prior year: EUR 22.8 million), driven by higher R&D costs for HDP-101.

  • Net loss widened to EUR 21.1 million from EUR 14.3 million year-over-year; EPS at EUR -0.45 (prior year: EUR -0.31).

  • Cash at period end was EUR 22.9 million, down from EUR 36.6 million a year earlier.

Outlook and guidance

  • 2025 sales and other income expected between EUR 7.5–9 million (previously EUR 9–11 million).

  • Operating expenses forecasted at EUR 36–40 million (previously EUR 40–45 million).

  • EBIT expected between EUR -28.5 million and EUR -31 million.

  • Cash requirements for 2025 estimated at EUR 14–17 million; financing secured until mid-2026.

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Frequently asked questions

Heidelberg Pharma is a biopharmaceutical company that focuses on oncology and antibody targeted amanitin conjugates (ATAC). Their innovations are based on cell immunotherapy and the drug amanitin conjugates (ATAC). The tumor cells are attacked by immune cells, which recognize the amanitin antigen as a foreign body. This way the treatment causes no mutilation of healthy tissue.

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