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Ikena Oncology (IKNA) investor relations material

Ikena Oncology Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary24 Jul, 2025

Executive summary

  • Entered into a merger agreement with Inmagene Biopharmaceuticals, with stockholder approval obtained in July 2025; closing expected by end of July, subject to remaining conditions.

  • Discontinued development of IK-930 and began winding down IK-595 clinical program in July 2025, shifting focus to strategic alternatives and asset divestitures.

  • Net loss for the six months ended June 30, 2025 was $11.4 million, a significant improvement from $29.9 million in the same period last year.

  • Cash, cash equivalents, and marketable securities totaled $95.6 million as of June 30, 2025, expected to fund operations for at least 12 months if the merger is not consummated.

  • Company’s future operations are highly dependent on successful completion of the merger or another strategic transaction.

Financial highlights

  • Net loss for Q2 2025 was $2.8 million, compared to $13.8 million in Q2 2024; six-month net loss was $11.4 million, down from $29.9 million year-over-year.

  • Operating expenses for the six months ended June 30, 2025 decreased 43% year-over-year to $19.5 million, driven by lower R&D and G&A costs.

  • Research and development expenses fell 60% year-over-year to $7.7 million for the six months ended June 30, 2025.

  • General and administrative expenses decreased 11% year-over-year to $10.1 million for the six months ended June 30, 2025.

  • Other income for the six months ended June 30, 2025 was $8.2 million, including $4.3 million in R&D reimbursements and $0.8 million in sublease income.

Outlook and guidance

  • If the merger closes, the combined company will focus on advancing Inmagene’s lead candidate, IMG-007, in atopic dermatitis and other immunology indications.

  • If the merger or another strategic transaction is not completed, the board may pursue dissolution and liquidation, with cash available for distribution dependent on timing and liabilities.

  • Ongoing costs expected for merger-related activities and strategic review; additional funding may be needed if development resumes.

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Frequently asked questions

Ikena Oncology is a U.S.-based biopharmaceutical company focused on developing innovative therapies targeting cancer and other immune-related diseases. The company's research centers on molecular mechanisms that drive tumor growth and immune evasion, with a focus on precision oncology and immuno-oncology approaches. Ikena’s pipeline includes treatments aimed at targeting key signaling pathways involved in cancer progression, with therapies designed to offer new options for patients with difficult-to-treat cancers. The company is headquartered in Boston, Massachusetts, and its shares are listed on NASDAQ.

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