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ImageneBio
ImageneBio (IMA) investor relations material
ImageneBio H.C. Wainwright 28th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 28th Annual Global Investment Conference summary14 Sep, 2026
Company and lead asset overview
Headquarters located in Del Mar, San Diego, with Olevaprubart (Oleva) as the lead program targeting OX40 for atopic dermatitis and alopecia areata.
Olevaprubart is a next-generation, receptor-directed monoclonal antibody, engineered for high differentiation and efficacy.
Differentiation and clinical rationale
Olevaprubart targets the OX40 receptor, is non-T cell depleting, and has a long half-life, enabling patient-friendly dosing intervals.
The antibody silences ADCC function, preserving T cells and reducing adverse events seen with prior OX40-targeting drugs.
Ongoing phase IIb adaptive study evaluates monthly and quarterly dosing, with potential for even wider intervals.
Safety and risk mitigation
No cases of Kaposi sarcoma observed in trials; study design includes careful patient selection and monitoring for HHV-8.
Investigator training and inclusion/exclusion criteria aim to minimize risk, with ongoing vigilance for safety signals.
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Latest events from ImageneBio
- Up to $200M in securities registered, including $17M at-the-market sales via Jefferies.IMA
Registration filing - Registering 5.77M shares for resale from a $30M private placement; no proceeds to the company.IMARegistration filing
- Net loss rose to $20.8 million as clinical pipeline advanced and cash reserves support operations into 2028.IMAQ2 2026
- Net loss narrowed to $49.2M as merger with Inmagene and IK-595 prioritization shaped 2024.IMAQ4 2024
- Net loss narrowed sharply as the company pivots to a merger-focused strategy and winds down R&D.IMAQ2 2025
- Q2 net loss narrowed on lower R&D spend; strategic review and cash runway extend into 2025.IMAQ2 2024
- Q3 net loss was $24.8M as IMG-007 advanced in trials and cash reached $142.6M.IMAQ3 2025
- Strong cash position and advancing clinical trial for IMG-007 with robust safety data.IMAQ4 2025
- Q1 2026 net loss was $10.6M, with $117.2M in cash and IMG-007 advancing in two indications.IMAQ1 2026
Next ImageneBio earnings date
Q3 20265 Nov, 2026
ImageneBio
Next ImageneBio earnings date
Q3 20265 Nov, 2026
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