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Investor Relations14 Oct 2025
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Imugene (IMU) investor relations material
Imugene H2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H2 2025 earnings summary25 Aug, 2025
Executive summary
Achieved significant clinical progress, notably with azer-cel, which showed a 79% response rate in Phase 1b DLBCL trials and received FDA Fast Track Designation, with trial expansion into rare lymphomas and first Australian patient dosed.
Advanced onCARlytics and VAXINIA programs, with VAXINIA receiving FDA Orphan Drug Designation for biliary tract cancer and PD1-Vaxx entering Phase II trials for colorectal cancer.
Strengthened leadership with new CFO and CMO appointments; implemented cost-saving measures, reducing headcount and administrative expenses.
Financial highlights
Net loss for FY25 was $68.97 million, a 54% improvement from FY24's $149.68 million loss.
General and administrative expenses reduced by 54%, R&D expenses by 46%, and cash outflows to suppliers and employees by 12%.
Cash reserves at 30 June 2025 were $21.94 million, prior to receiving $5.87 million in R&D tax incentives and $22.52 million from a new share placement in July 2025.
Outlook and guidance
Focus on progressing azer-cel to pivotal Phase 2 trials in CY26, with additional Phase 1b data and trial expansion into CAR T naïve lymphoma patients expected in Q3/Q4 2025.
Anticipated FDA End-of-Phase meeting in Q4 2025 to confirm registrational trial pathway.
Key outcomes from Q4 CY25 FDA discussions?
Future cost reduction strategies beyond headcount?
Pipeline strategy for non-Azer-cel assets?
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Next Imugene earnings date
Q1 202627 Nov, 2025
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Frequently asked questions
Imugene Limited is an Australian biotechnology company focused on developing immunotherapies for the treatment of cancer. The company’s research is centered around activating the immune system to target and eliminate cancer cells, utilizing a range of technologies, including oncolytic viruses and B-cell activating immunotherapies. Imugene’s clinical pipeline includes treatments for various cancer types, and the company works on advancing its therapies through preclinical and clinical development stages. The company is headquartered in Sydney, Australia, and its shares are listed on the ASX.
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