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Imunon (IMNN) investor relations material
Imunon Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary13 Nov, 2025
Executive summary
OVATION 3 Phase III trial for IMNN-001 in advanced ovarian cancer is enrolling ahead of plan, with strong investigator enthusiasm and promising interim and Phase 2 data showing improved survival and safety.
Recent R&D day and major oncology conference presentations highlighted the transformative potential of IMNN-001 and the significant unmet need in ovarian cancer.
The MRD Phase II study continues to show favorable safety and efficacy, supporting future label extensions and attracting external funding.
PlaCCine DNA vaccine platform completed Phase 1 trial for COVID-19 booster, demonstrating safety, durable immunogenicity, and ongoing partnership efforts.
Financial highlights
Net loss for Q3 2025 was $3.4 million ($1.16/share), improved from $4.8 million ($3.76/share) in Q3 2024; nine-month net loss was $10.3 million ($5.53/share), down from $14.6 million ($14.13/share) year-over-year.
Cash and cash equivalents were $5.3 million as of September 30, 2025, with $4.5 million raised in Q3 through warrant exercises and ATM usage.
R&D expenses for Q3 2025 were $1.9 million, down from $3.3 million year-over-year; G&A expenses were $1.6 million, down from $1.7 million.
For the nine months ended September 30, 2025, R&D expenses were $5.3 million (down 44%), and G&A expenses were $5.1 million (down 9%) year-over-year.
Cash runway extends into mid-Q1 2026, with monthly cash burn at $1.25–$1.5 million.
Outlook and guidance
Full enrollment in OVATION 3 is estimated by late 2028, with potential acceleration if additional financing is secured.
Management plans to raise additional capital through equity offerings, partnerships, or strategic transactions, with no revenue expected from product sales in the next several years.
Multiple near-term catalysts include enrollment momentum, regular scientific presentations, and potential partnership progress.
Sufficient capital resources to fund planned operations into Q1 2026, but substantial doubt remains about the ability to continue as a going concern without new funding.
Accelerate OVATION 3 enrollment timeline
Detail operating expense reduction strategy
IMNN-001's systemic IL-12 toxicity avoidance
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Frequently asked questions
Imunon Inc. is a clinical-stage biotechnology company focused on the development of innovative therapies for oncology and infectious diseases. The company utilizes its proprietary ThermoDox platform, which combines heat-activated liposomal drug delivery with targeted chemotherapy to enhance treatment effectiveness. Imunon also engages in the development of DNA-based vaccines and immunotherapies aimed at improving patient outcomes. The company is headquartered in Lawrenceville, New Jersey, and its shares are listed on the NASDAQ.
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