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Innate Pharma (IPH) investor relations material
Innate Pharma Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary17 Sep, 2025
Executive summary
Strategic focus on advancing IPH4502, lacutamab, and monalizumab, with organizational streamlining and a planned 30% workforce reduction to prioritize resources.
€15m equity investment by Sanofi in April 2025, strengthening the partnership and capital base.
Corporate governance changes include a shift to a CEO/board structure, new board appointments, and establishment of an R&D Committee.
Emphasis on leveraging differentiated antibody engineering, innate immunity, and clinical data to advance transformative cancer therapies.
Chief Scientific Officer Eric Vivier transitioned to an advisory role, with Yannis Morel assuming CSO responsibilities.
Financial highlights
Cash, cash equivalents, and financial assets totaled €70.4m as of June 30, 2025, down from €91.1m at year-end 2024, supporting operations through Q3 2026.
Revenue and other income for H1 2025 was €4.9m, mainly from collaborations with AstraZeneca and Sanofi, and government research funding.
Operating expenses decreased to €30.3m (H1 2025), with R&D expenses at €20.5m (67.8% of total), down €8.6m year-over-year.
Net loss of €21.3m for H1 2025, compared to a net loss of €24.8m in H1 2024.
Net financial gain of €4.1m in H1 2025, mainly from favorable foreign exchange movements.
Outlook and guidance
Cash runway expected until end of Q3 2026, including impact of restructuring.
Key milestones: first patient data for IPH4502 in H1 2026, preliminary safety/activity data in H1 2026, and high-level readout of PACIFIC-9 Phase 3 trial with monalizumab in H2 2026.
Lacutamab Phase 3 protocol near completion; trial initiation targeted for 2026 pending financing or partnership, with potential accelerated approval in 2027.
Streamlining and organizational changes to be completed in H1 2026.
Lacutamab Phase III financing strategy
IPH4502 differentiation vs. other Nectin-4 ADCs
Future R&D allocation post strategic refocus
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Next Innate Pharma earnings date
Q3 2025 TU13 Nov, 2025
Next Innate Pharma earnings date
Q3 2025 TU13 Nov, 2025
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Frequently asked questions
Innate Pharma S.A., a biotechnology company, discovers, develops, and commercializes therapeutic antibodies for the treatment of oncology indications. It generates its products from the expression platforms based on its phage display and dAb technologies. The company's lead product is NexoBrid, which is a treatment for severe burns that can be used outside of the European Union; and Phase 3 NExoBrid clinical trial is completed in Europe. Innate Pharma S.A. was founded in 2000 as Innate ImmunoPharmaceuticals S.A.; and it changed its name to Innate Pharma S.A. in 2011. Innate Pharma S.A. has operations in Saint Prex, Switzerland; and Sophia Antipolis, France. Innate Pharma S.A is based in Marseille, France.
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