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Innoviva (INVA) investor relations material

Innoviva Piper Sandler 37th Annual Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Piper Sandler 37th Annual Healthcare Conference summary2 Dec, 2025

Business overview and strategy

  • Operates a diversified model with royalty-based respiratory assets, a fast-growing specialty therapeutics business, and a strategic healthcare investment portfolio valued at $500 million.

  • Royalty business generates about $250 million annually from Breo and Anoro, with strong patent protection into the early 2030s.

  • Specialty therapeutics (IST) delivers over $100 million in revenue, growing rapidly, driven by differentiated hospital products.

  • Strategic investments target disruptive healthcare assets with high upside and downside protection.

  • Maintains flexibility in capital deployment, open to opportunistic royalty acquisitions and synergistic hospital assets.

Specialty therapeutics (IST) growth drivers

  • Giapreza leads revenue, benefiting from refreshed commercial strategy and new clinical data expanding use cases.

  • Xacduro addresses significant unmet need in resistant Acinetobacter infections, showing strong launch performance.

  • Xerava benefits from resistance trends and remains relevant despite being a mature product.

  • Zevtera, recently launched, targets Staph aureus bacteremia and is expected to ramp as access expands.

  • All IST products have patent protection into the 2030s, with no near-term exclusivity losses.

Commercial and market access strategy

  • Hospital launches require navigation of stewardship and P&T committees, but differentiated products ease access.

  • Zevtera is positioned as an early option for challenging bacteremia cases, with skin and pneumonia indications seen as upside.

  • Giapreza is increasingly used earlier in ICU shock, with expanding adoption in new patient populations.

  • Zoliflodacin, pending approval, offers oral therapy for resistant gonorrhea, with commercialization likely to leverage guidelines and a lean sales model.

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Frequently asked questions

Innoviva Inc. is a biopharmaceutical company focused on managing and developing royalty portfolios. The company's primary business involves the commercialization of its portfolio of royalties, primarily derived from partnerships with pharmaceutical companies. Innoviva's portfolio includes interests in respiratory medicines and other therapeutic areas, where it receives royalties from the sale of these products. The company is involved in actively managing its royalty portfolio and exploring potential acquisitions or partnerships to expand its interests in healthcare assets. The company is headquartered in Burlingame, California, and its shares are listed on the NASDAQ.

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