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Intra-Cellular Therapies (ITCI) investor relations material
Intra-Cellular Therapies Q4 2024 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
CAPLYTA net product sales reached $199.2M in Q4 2024, up 51% year-over-year; full-year 2024 sales were $680.5M, a 47% increase.
FDA accepted the sNDA for lumateperone as adjunctive treatment for major depressive disorder (MDD).
Field sales force expansion began in Q1 2025 in anticipation of potential MDD approval.
Financial highlights
SG&A expenses rose to $504.5M in 2024 from $409.9M in 2023, mainly due to commercialization and marketing.
R&D expenses increased to $236.1M in 2024 from $180.1M in 2023, reflecting higher project costs.
Cash, cash equivalents, investment securities, and restricted cash totaled $1.0B at year-end 2024, up from $499.7M at year-end 2023.
Net loss for Q4 2024 was $16.9M ($0.16/share); full-year net loss was $74.7M ($0.72/share), improved from $139.7M loss in 2023.
Outlook and guidance
Anticipates potential FDA approval and commercial launch of CAPLYTA for adjunctive MDD treatment.
Ongoing expansion of sales force to support expected growth.
- Lumateperone showed robust efficacy and safety as adjunctive therapy in MDD Phase 3 trials.ITCI
Study Result3 Feb 2026 - Caplyta sales surged 46% in Q2 2024, driving improved results and a higher 2024 outlook.ITCI
Q2 20242 Feb 2026 - MDD sNDA filing expected this year, with pipeline and sales force expansion progressing.ITCI
Canaccord Genuity 44th Annual Growth Conference & Private Company Showcase 20242 Feb 2026 - Strong growth in mood disorders, pipeline expansion, and robust prescriber base drive outlook.ITCI
Goldman Sachs 45th Annual Global Healthcare Conference1 Feb 2026 - CAPLYTA's growth accelerates with new indications, pivotal trials, and strong financials.ITCI
Jefferies 2024 Global Healthcare Conference1 Feb 2026 - CAPLYTA's strong growth and clinical success drive expansion into MDD and broader CNS markets.ITCI
Morgan Stanley 22nd Annual Global Healthcare Conference22 Jan 2026 - CAPLYTA’s growth accelerates with new indications and a rich pipeline, backed by strong finances.ITCI
Baird's 2024 Global Healthcare Conference21 Jan 2026 - Caplyta's robust growth and broadening indications drive major expansion into mood disorder markets.ITCI
2024 Cantor Fitzgerald Global Healthcare Conference20 Jan 2026 - Q3 2024 net sales up 39% year-over-year; guidance raised on strong growth and pipeline.ITCI
Q3 202417 Jan 2026 - MDD approval is set to accelerate growth, supporting a $5B market opportunity in five years.ITCI
7th Annual Evercore ISI HealthCONx Conference12 Jan 2026
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