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Invivyd (IVVD) investor relations material
Invivyd H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Company overview and technology platform
Focuses on monoclonal antibodies for viral diseases, starting with COVID-19.
Proprietary platform enables rapid development and adaptation of antibodies.
PEMGARDA, an IV-administered antibody, targets immunocompromised patients.
Next-generation antibody VYD-2311 aims for intramuscular delivery and longer durability.
Pipeline includes programs for RSV and measles.
Product performance and differentiation
PEMGARDA maintains efficacy across COVID-19 variants, unlike some competitors.
VYD-2311 offers improved half-life, potency, and potential for less frequent dosing.
Intramuscular administration could increase patient access and convenience.
Phase 1/2 data show a 76-day half-life and strong safety profile for VYD-2311.
VYD-2311 demonstrates a 17-fold potency improvement over PEMGARDA.
Regulatory and clinical development
Positive engagement with FDA following changes in administration and leadership.
Type C meeting supports a single pivotal Phase 2/3 trial for VYD-2311 BLA submission.
IND opening and trial enrollment for VYD-2311 expected in coming quarters.
Plans to present data to FDA by late Q2 or early Q3 next year.
Exploring head-to-head studies versus vaccines and potential for treatment indications.
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