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IRLAB Therapeutics (IRLAB) investor relations material

IRLAB Therapeutics Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary27 Aug, 2025

Executive summary

  • Advanced pipeline with five drug candidates for Parkinson's and CNS diseases, including three in clinical and two in preclinical development, with key milestones such as positive Phase I results for IRL757 and a new US patent for mesdopetam extending exclusivity into the 2040s.

  • Significant progress in patent protection, especially for Mestopetam, securing exclusivity into the mid-2040s in major markets.

  • Strengthened financial position through rights issues raising SEK 60 million and SEK 115.7 million, and expanded loan agreements.

  • Focused on advancing partnerships and licensing agreements to realize commercial value from the drug portfolio.

  • Leadership transition with CFO Viktor Siewertz departing and an interim CFO appointed.

Financial highlights

  • Cash and cash equivalents at period end were SEK 54 million, bolstered by rights issues, but down from SEK 98 million year-over-year.

  • Net sales for Jan–Jun 2025 were SEK 24 million, entirely from the Otsuka collaboration for IRL757, down from SEK 42.8 million year-over-year.

  • Operating loss widened to SEK -54.4 million, with a period loss of SEK -66.3 million and negative equity of SEK -27.7 million.

  • R&D costs accounted for 80% of total operating expenses in H1 2025.

  • External clinical costs decreased in May and June, with increased investment in IRL757 as new studies commence.

Outlook and guidance

  • Phase III initiation planned for Mestopetam, pending partnership.

  • IRL757 study in Parkinson’s apathy to begin dosing in Q4, with results expected in 18 months and first patient recruitment in Q4 2025.

  • 11/17 preclinical work prioritized, aiming for Phase I start in late 2025 or early 2026.

  • Ongoing efforts to secure revenue-generating partnerships and licensing deals for advanced drug candidates.

  • Focus on optimizing development plans for pirepemat and IRL1117, with further studies planned.

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Frequently asked questions

IRLAB Therapeutics AB is a research and development company developing drugs for the treatment of Parkinson's disease. IRLAB develops drugs that can stop or slow down the loss of neurons in the substantia nigra, where dopamine is produced. In Parkinson's disease, loss of these neurons leads to a gradual degeneration of the motor functions. These drugs will improve symptoms without dramatically increasing the risk of side effects.

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