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IRLAB Therapeutics
IRLAB Therapeutics (IRLAB) investor relations material
IRLAB Therapeutics Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q4 2025 earnings summary25 Feb, 2026
Executive summary
Advanced Parkinson's disease pipeline with multiple assets in clinical and preclinical stages, including IRL757, mesdopetam, pirepemat, IRL942, and IRL1117.
IRL757 advanced to Phase Ib for apathy in Parkinson's, with all clinical sites activated, recruitment ongoing, and study fully funded through MSRD/Otsuka collaboration.
Mesdopetam completed key milestones, with Phase III program design aligned with FDA and EMA, strong market interest, and new patents granted in US, EU, and China.
Pirepemat demonstrated significant reduction in fall rates in Phase IIb, with expert support for further development and regulatory strategy underway.
Strategic partnerships and business development intensified, including collaboration with Biomia to expand CNS drug discovery using the ISP platform.
Financial highlights
Net sales for 2025 were SEK 57.5 million, down from SEK 94.6 million in 2024; Q4 net sales SEK 14.7 million vs. SEK 42.8 million prior year.
Operating loss widened to SEK -93.4 million from SEK -75.1 million; Q4 operating loss SEK -21.9 million vs. SEK -3.0 million.
Cash and cash equivalents at year-end were SEK 82 million, up from SEK 66.9 million.
Cash flow from operating activities improved to SEK -55.2 million from SEK -65.6 million.
Loss for the year was SEK -110.0 million, compared to SEK -83.1 million in 2024.
Outlook and guidance
Focus on securing partnerships and financing for Phase III mesdopetam and further development of pirepemat.
IRL757 Phase Ib study execution and evaluation to guide next steps.
IRL1117 preclinical development to advance toward Phase I readiness.
Actively seeking collaborations and licensing deals to secure future funding.
Continued prioritization of resource efficiency and strategic innovation.
Mesdopetam Phase III funding strategy
Pirepemat dose optimization for Phase III
Impact of cost base reduction on operations
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Next IRLAB Therapeutics earnings date
Life Science-dagen 20264 Mar, 2026
IRLAB Therapeutics
Next IRLAB Therapeutics earnings date
Life Science-dagen 20264 Mar, 2026
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Frequently asked questions
IRLAB Therapeutics AB is a research and development company developing drugs for the treatment of Parkinson's disease. IRLAB develops drugs that can stop or slow down the loss of neurons in the substantia nigra, where dopamine is produced. In Parkinson's disease, loss of these neurons leads to a gradual degeneration of the motor functions. These drugs will improve symptoms without dramatically increasing the risk of side effects.
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