Kymera Therapeutics
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Kymera Therapeutics (KYMR) investor relations material

Kymera Therapeutics Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary29 Oct, 2026

Executive summary

  • KT-579 Phase 1 showed median IRF5 degradation of at least 90%, broad biomarker effects across immune pathways and placebo-like safety; a lupus Phase 1b study is planned for early 2027.

  • KT-621 is in Phase 2b trials for atopic dermatitis and asthma; AD results are expected by year-end 2026 and asthma results in late 2027.

Financial highlights

  • Q3 2026 collaboration revenue was $0, versus $2.764 million in Q3 2025; no additional collaboration revenue is expected in 2026.

  • Q3 R&D expense was $128.509 million versus $74.094 million; G&A was $18.7 million versus $17.3 million.

  • Q3 net loss was $131.999 million versus $82.175 million; nine-month net loss was $262.444 million versus $224.370 million.

  • Nine-month collaboration revenue was $99.365 million versus $36.341 million, reflecting recognized Gilead and Sanofi milestones.

  • Q3 adjusted cash G&A was $10.8 million, down 14% QoQ; R&D excluding non-cash stock-based compensation was $117.6 million, up 8% QoQ.

Outlook and guidance

  • KT-621 BROADEN2 AD topline data are expected by year-end 2026; Phase 3 initiation is targeted by mid-2027, subject to supportive data and FDA alignment.

  • KT-621 BREADTH asthma Phase 2b results are expected in late 2027; KT-579 LUMORA lupus Phase 1b is planned to start by early 2027.

  • LUMORA is planned as a randomized, double-blind, placebo-controlled 16-week biomarker study in ~30 adults with SLE, allocated 2:1 to KT-579 or placebo.

  • Gilead is conducting IND-enabling studies for KT-200, with an IND filing planned for 2027; Sanofi leads KT-485 development in Phase 1.

  • Cash runway is expected to extend into 2029; R&D and G&A expenses are expected to rise as clinical development advances.

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Frequently asked questions

Kymera Therapeutics, Inc. is a biopharmaceutical company focused on discovering and developing targeted protein degradation therapies. The company’s proprietary platform aims to design small-molecule drugs that selectively degrade disease-causing proteins, offering a novel approach to treating conditions that have been difficult to address with traditional therapies. Kymera Therapeutics is engaged in research and development across various therapeutic areas, including oncology, immunology, and inflammation. The company is headquartered in Watertown, United States, and its shares are listed on the NASDAQ.