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Kymera Therapeutics (KYMR) investor relations material
Kymera Therapeutics Evercore ISI 8th Annual HealthCONx Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Evercore ISI 8th Annual HealthCONx Conference summary4 Dec, 2025
Company overview and strategic focus
Celebrating 10-year anniversary in May, with a focus on targeted protein degradation for unmet medical needs.
Central focus on immunology markets due to large opportunities and limitations of current biologics.
Five programs have entered the clinic, with STAT6 as the current primary focus.
Pipeline includes two partnered programs, one wholly owned, and more in development for future disclosure.
STAT6 program development and clinical progress
Phase 2b study initiated, informed by Phase 1a PK/PD data and preliminary Phase 1b results.
Phase 2b is a dose range finding study with three dose levels and placebo, enrolling 200 patients globally.
Phase 1b provides confirmatory evidence for dose selection and supports investigator enthusiasm for Phase 2b.
Data from Phase 1b, including safety, biomarkers, and clinical outcomes, will be disclosed soon.
Phase 2b atopic dermatitis study has started; asthma study to begin in Q1 next year.
Clinical endpoints, safety, and expectations
Primary endpoint for Phase 2b is mean percent change in EASI at 16 weeks; data expected by mid-2027.
Both continuous (mean EASI) and categorical (EASI-50, EASI-75) endpoints will be reported.
Rapid onset of action expected, with peak degradation seen within hours of dosing.
Safety profile anticipated to mirror Dupixent, with conjunctivitis as a possible but non-limiting adverse event.
Placebo-like safety observed in Phase 1a and preclinical studies, supporting high selectivity and potency.
Oral STAT6: Key advantages over current biologics?
IRF5: Which disease indication for first patient study?
How to interpret EASI-50/75 in small N Phase 1b?
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Next Kymera Therapeutics earnings date
Q4 202526 Feb, 2026
Next Kymera Therapeutics earnings date
Q4 202526 Feb, 2026
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Frequently asked questions
Kymera Therapeutics, Inc. is a biopharmaceutical company focused on discovering and developing targeted protein degradation therapies. The company’s proprietary platform aims to design small-molecule drugs that selectively degrade disease-causing proteins, offering a novel approach to treating conditions that have been difficult to address with traditional therapies. Kymera Therapeutics is engaged in research and development across various therapeutic areas, including oncology, immunology, and inflammation. The company is headquartered in Watertown, United States, and its shares are listed on the NASDAQ.
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