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Kyowa Kirin (4151) investor relations material
Kyowa Kirin Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary30 Oct, 2025
Executive summary
Revenue for Jan–Sep 2025 was ¥349.5B, down 3.7% year-over-year, mainly due to APAC restructuring and drug price reductions, with overseas sales comprising 73% of total revenue.
Core operating profit declined 16.7% to ¥62.0B, and net profit dropped 41.7% to ¥32.6B, reflecting lower core profit and absence of prior-year one-time gains.
Major revenue drivers included Crysvita (+9% YoY), Poteligeo (+16% YoY), and Libmeldy/Lenmeldy (+103% YoY), while Japan sales fell due to Dobovet partnership termination and NHI price cuts.
North America and EMEA saw growth in strategic products, while APAC/Other revenue dropped due to restructuring.
Profit before tax was ¥47.9B (down 33.0%), and basic EPS was ¥62.28 (down from ¥105.20 YoY).
Financial highlights
Gross profit margin remained stable at 74%, but gross profit decreased by 3% YoY.
SG&A expenses decreased 2% YoY, reflecting APAC business restructuring.
R&D expenses increased 3% YoY to ¥76.8B, driven by consolidation of Orchard and pipeline progress.
Negative forex impact reduced revenue by ¥3.9B and core OP by ¥2.3B.
Cash and cash equivalents at period end: ¥240.2B; net cash from operating activities: ¥69.6B.
Outlook and guidance
FY2025 revenue guidance is ¥478.0B, with 73% progress to goal as of Q3.
Core OP margin is expected to be 17% for FY2025; core OP forecast: ¥80.0B.
Net profit forecast: ¥57.0B; R&D ratio projected at 22% for the full year.
No revisions to previously announced forecasts.
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Q4 20256 Feb, 2026
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Frequently asked questions
Kyowa Kirin Co., Ltd. is a Japanese pharmaceutical company engaged in the research, development, manufacturing, and marketing of biopharmaceutical and pharmaceutical products. The company focuses on therapeutic areas including oncology, nephrology, immunology, and the central nervous system, aiming to address complex medical needs. Kyowa Kirin leverages biotechnology and antibody research to develop treatments for patients globally, with products available through prescription channels and hospital networks. The company is headquartered in Tokyo, Japan, and its shares are listed on the TSE.
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