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Investor Relations14 Oct 2025
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Kyowa Kirin (4151) investor relations material
Kyowa Kirin Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary1 Aug, 2025
Executive summary
Revenue for the first half of 2025 was ¥230.7 billion, down 1% year-over-year, with overseas sales ratio rising to 73%.
Core operating profit declined 21% to ¥35.0 billion, and net profit dropped 57% to ¥16.3 billion, mainly due to restructuring and special retirement expenses.
Overseas revenue growth, especially in North America and EMEA, partially offset declines in Japan and APAC.
Growth in key products Crysvita (+10% YoY) and Poteligeo (+14% YoY) offset by declines in Japan from partnership terminations and NHI price cuts.
R&D expenses increased 7% YoY, reflecting pipeline progress and new consolidation of Orchard.
Financial highlights
Gross profit margin fell to 73%, with gross profit at ¥168.8 billion, down from ¥173.5 billion YoY.
Core operating profit margin dropped to 15% from 19% YoY.
Net profit fell by ¥21.5 billion (-57%) year-over-year, mainly due to restructuring costs and FX losses.
R&D expenses rose to ¥52.5 billion, with R&D ratio at 23% of revenue, up from 21% YoY.
EBITDA profit decreased by ¥21.5 billion year-over-year.
Outlook and guidance
Full-year 2025 revenue forecast is ¥478.0 billion, with 48% progress achieved by mid-year.
Core operating profit guidance is ¥80.0 billion (44% progress), and net profit guidance is ¥57.0 billion (29% progress).
Management remains confident in achieving full-year targets despite headwinds.
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Next Kyowa Kirin earnings date
Q3 202530 Oct, 2025
Next Kyowa Kirin earnings date
Q3 202530 Oct, 2025
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Frequently asked questions
Kyowa Kirin Co., Ltd. is a Japanese pharmaceutical company engaged in the research, development, manufacturing, and marketing of biopharmaceutical and pharmaceutical products. The company focuses on therapeutic areas including oncology, nephrology, immunology, and the central nervous system, aiming to address complex medical needs. Kyowa Kirin leverages biotechnology and antibody research to develop treatments for patients globally, with products available through prescription channels and hospital networks. The company is headquartered in Tokyo, Japan, and its shares are listed on the TSE.
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