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Lantern Pharma (LTRN) investor relations material

Lantern Pharma Investor Update summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Investor Update summary26 Aug, 2025

Business and operational overview

  • Focuses on AI-driven development of precision oncology medicines, with three clinical-stage small molecules and a robust preclinical pipeline, including antibody drug conjugates.

  • Maintains a disciplined fiscal profile with a quarterly burn rate of $4.5M, cash runway into 2026, no debt, and approximately 12M fully diluted shares.

  • Holds 11 FDA designations (5 orphan, 4 rare pediatric, 2 fast track) and about 140 issued and pending patents covering composition, methods, and AI platform innovations.

  • Business model centers on early innovation, rapid execution, and out-licensing assets to larger pharma partners.

Clinical pipeline and trial updates

  • LP-300 in Phase II targets never-smoker non-small cell lung cancer, a $4–5B global market, with strong early data and expansion into Japan and Taiwan.

  • LP-184 completed Phase I enrollment (65 patients) across multiple solid tumors; moving to Phase Ib/II in TNBC, STK11/KEAP1-mutated lung cancer, and bladder cancer.

  • LP-284, a sister drug to LP-184, is in trials for B-cell lymphomas, showing a complete metabolic response in a patient who failed multiple prior therapies.

  • Combination therapy strategies are a major focus, with promising preclinical synergy between LP-184 and PARP inhibitors in TNBC and checkpoint inhibitors in lung cancer.

AI platform and technology strategy

  • AI platform (RADAR) is central to drug discovery, enabling rapid, iterative modeling and prediction for molecule selection, trial design, and combination strategies.

  • Public release of PredictBBB.ai module allows users to predict blood-brain barrier penetrability with high accuracy, supporting both internal and external collaborations.

  • Future modules will expand predictive capabilities to additional molecular properties, aiming to disrupt traditional drug development timelines and costs.

  • AI platform is being commercialized via a freemium model, with free trials and paid tokens or collaborations for extended use.

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Q3 202514 Nov, 2025
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Frequently asked questions

Lantern Pharma Inc. is a clinical-stage biotechnology company focused on leveraging artificial intelligence and genomic data to develop precision oncology therapeutics. The company’s pipeline targets a range of cancers with the aim of enhancing treatment outcomes and reducing development risks. Lantern Pharma Inc. is headquartered in Dallas, Texas, and its shares are listed on the NASDAQ.

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