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Lantheus (LNTH) investor relations material
Lantheus Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary6 Nov, 2025
Executive summary
Q3 2025 revenue was $384 million, up 1.4% year-over-year, with adjusted EPS at $1.27, GAAP EPS at $0.41, and net income down 78.8% due to pricing pressures and higher expenses.
Leadership transition announced: CEO retiring at year-end, interim CEO appointed, and President departing; Board conducting CEO search.
Completed acquisitions of Life Molecular Imaging ($355.2M upfront, up to $400M earn-out) and Evergreen Theragnostics ($276.4M upfront, up to $727.5M contingent), expanding the commercial portfolio and pipeline.
Entered agreement to sell SPECT business, classified as held for sale as of September 30, 2025.
Four major product approvals anticipated by end of 2026, including new PET imaging agents and radiotherapeutics.
Financial highlights
Q3 2025 net revenue was $384 million (+1.4% YoY); adjusted EPS was $1.27 (-25.3% YoY); GAAP EPS was $0.41 (-77.1% YoY).
PYLARIFY sales were $240.6 million, down 7.4% YoY; DEFINITY sales were $81.8 million, up 6.3% YoY; Neuraceq sales reached $20.4 million, up 100% YoY.
Precision diagnostics revenue rose 25% to $129.7 million; TechneLite revenue up 3.2% to $21.1 million.
Gross profit margin was 63.5% (non-GAAP) and 57.9% (GAAP), both down from prior year; operating income was $43.6 million, down 67.4% YoY.
Free cash flow was $94.7 million; cash and equivalents at quarter-end were $382 million; $750 million undrawn revolver available.
Outlook and guidance
Full-year 2025 revenue guidance narrowed to $1.49–$1.51 billion; adjusted EPS guidance narrowed to $5.50–$5.65.
Four key product approvals expected by end of 2026, including new F-18 PSMA PET and tau imaging agents.
PYLARIFY and Neuraceq expected at higher end of prior guidance ranges; low single-digit PYLARIFY volume growth expected, offset by price compression.
Sale of SPECT business expected to close by year-end 2025.
Impact of leadership changes on company strategy?
New PYLARIFY formulation: TPT status outlook?
Acquisition strategy for pipeline diversification?
Impact of leadership changes on strategy
F-18 PSMA PET formulation benefits
MK-6240 differentiation in tau imaging?
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Frequently asked questions
Lantheus Holdings Inc. is a healthcare company specializing in diagnostic imaging and therapeutic solutions. The company develops and commercializes radiopharmaceuticals, contrast agents, and medical imaging products used in cardiology, oncology, and other critical care applications. Lantheus serves healthcare providers, hospitals, and imaging centers, focusing on technologies that enhance disease detection and patient management. Its portfolio includes products for nuclear medicine, ultrasound, and precision diagnostics. The company is headquartered in Bedford, Massachusetts, and its shares are listed on the NASDAQ.
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