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Investor Relations14 Oct 2025
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Leap Therapeutics (LPTX) investor relations material
Leap Therapeutics Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary14 Aug, 2025
Executive summary
Reported updated clinical data from the DeFiance study showing statistically significant benefits for sirexatamab in certain colorectal cancer patient subgroups; final data to be presented at a future conference.
Initiated a process to explore strategic alternatives, including potential sale, partnership, or merger, and engaged a financial advisor to assist.
Implemented a workforce reduction of 75% to conserve cash and focus on corporate development, with estimated total costs of $4.5 million.
Completed patient treatment in the DeFiance trial.
Financial highlights
Net loss attributable to common stockholders was $16.6 million for Q2 2025, compared to $20.4 million in Q2 2024.
Net loss per share was $0.40 for Q2 2025, compared to $0.52 for Q2 2024.
Cash and cash equivalents were $18.1 million as of June 30, 2025, down from $47.2 million at December 31, 2024.
Research and development expenses decreased to $10.5 million in Q2 2025 from $17.9 million in Q2 2024.
General and administrative expenses fell to $1.8 million from $3.4 million year-over-year.
Outlook and guidance
Substantial doubt exists regarding the ability to continue as a going concern for at least the next 12 months without additional capital or a strategic transaction.
Board is exploring all strategic alternatives, including merger, asset sale, or additional funding, but no assurance of successful completion.
Further updates on the strategic review are expected in the coming weeks.
What is the estimated cost of the workforce reduction?
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Next Leap Therapeutics earnings date
Q3 202513 Nov, 2025
Next Leap Therapeutics earnings date
Q3 202513 Nov, 2025
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Frequently asked questions
Leap Therapeutics Inc. is a clinical-stage biopharmaceutical company that focuses on developing novel therapeutics for cancer treatment. The company's main activities involve acquiring and developing antibody therapies, particularly targeting cancer-specific pathways and cell surface molecules, while also activating the immune system against cancer cells. Leap Therapeutics is engaged in multiple ongoing clinical trials for its lead product candidates. The company is headquartered in Cambridge, Massachusetts, and its shares are listed on the NASDAQ.
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