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LENZ Therapeutics (LENZ) investor relations material

LENZ Therapeutics Morgan Stanley 23rd Annual Global Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Morgan Stanley 23rd Annual Global Healthcare Conference summary10 Sep, 2025

Company background and product development

  • Developed a non-invasive ophthalmic drop for presbyopia using aceclidine, an active ingredient previously marketed for glaucoma, now repurposed for near vision improvement.

  • Product approval achieved recently, following large phase 3 trials demonstrating broad efficacy.

Clinical efficacy and differentiation

  • Achieves pinhole pupil effect below two millimeters, critical for restoring near vision.

  • 93% of patients reached 20/40 vision or better within an hour, with 70% maintaining this at 10 hours.

  • Over 70% achieved three lines or greater near vision improvement at 30 minutes and three hours post-dose.

  • No negative impact on distance vision; some patients experienced improvement.

Commercial strategy and market segmentation

  • Three-pillar strategy: drive doctor recommendations, stimulate consumer demand, and ensure seamless product access.

  • 88-person sales force targets 13,000–15,000 doctors, focusing on optometrists based on learnings from prior market launches.

  • DTC campaign with celebrity endorsement planned for Q1, targeting high-interest segments like contact lens wearers, LASIK patients, and active aging consumers.

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Frequently asked questions

LENZ Therapeutics Inc. is a biopharmaceutical company that specializes in the development and commercialization of innovative ophthalmic therapies aimed at improving vision. The company's primary focus is on treating presbyopia, a common age-related condition that affects near vision. LENZ Therapeutics is currently advancing its lead product candidates, LNZ100 and LNZ101, which are in Phase III clinical trials. These products are aceclidine-based eye drops designed to restore near vision for individuals with presbyopia. The company is headquartered in Del Mar, California, and its shares are listed on the NASDAQ.

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