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Lineage Cell Therapeutics (LCTX) investor relations material
Lineage Cell Therapeutics H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 27th Annual Global Investment Conference summary8 Sep, 2025
Key announcements and pipeline updates
Announced new ILT1 initiative targeting type 1 diabetes, aiming to solve manufacturing scale challenges for islet cell therapy.
Hearing loss program partnered with William Demant Invest, securing multi-year development funding.
Lead program OpRegen for dry age-related macular degeneration is in Phase 2 with Roche and Genentech, under a $670M partnership.
Photoreceptor and undisclosed RND1 programs advanced, with IP unencumbered and new gene editing alliances formed.
Ongoing expansion into new indications, leveraging manufacturing expertise and strategic partnerships.
Clinical and manufacturing insights
OpRegen demonstrated durable anatomical and functional vision improvements in dry AMD, with effects persisting for years after a single administration.
Manufacturing platform enables scalable, pure cell production, critical for commercial viability and large-scale indications like diabetes.
Spinal cord injury program showed improved mobility and strong safety profile, with allogeneic, off-the-shelf cell therapy.
No cell rejection or tumor formation observed in long-term follow-up, reflecting advances in cell therapy safety and purity.
Manufacturing improvements have led to much purer cell populations, enhancing clinical outcomes and safety.
Strategic direction and future outlook
Focus on repeating success of lead program by applying platform to new therapeutic areas, moving from defensive to offensive strategy.
Partnerships are key to advancing early-stage programs and managing capital in a challenging biotech funding environment.
Ex vivo gene editing incorporated through new alliances, with rigorous analytical validation before patient administration.
Diabetes initiative aims to address the need for massive cell quantities, leveraging proprietary banking and differentiation modalities.
Company is investing in a long-term future, awaiting further data updates from ongoing clinical trials.
What is the ILT1 manufacturing scale-up plan
What OpRegen data update is expected from partners
How will new programs be funded and advanced
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Next Lineage Cell Therapeutics earnings date
Q3 202513 Nov, 2025
Next Lineage Cell Therapeutics earnings date
Q3 202513 Nov, 2025
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Frequently asked questions
Lineage Cell Therapeutics Inc is a biotechnology company developing cell-based therapies for degenerative diseases. The company focuses on regenerative medicine approaches for ophthalmology, neurology, and oncology, using proprietary cell manufacturing platforms. The company is headquartered in Carlsbad, California, and its shares are listed on the NYSE American.
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