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Lipocine (LPCN) investor relations material

Lipocine Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary5 Aug, 2025

Executive summary

  • Focused on oral drug delivery for CNS, liver, and hormone disorders, with a pipeline including LPCN 1154 (postpartum depression), LPCN 2401 (obesity/GLP-1 adjunct), LPCN 2101 (epilepsy), and others.

  • Initiated pivotal Phase 3 trial for LPCN 1154 in postpartum depression, with topline results expected Q2 2026 and NDA submission planned for mid-2026.

  • Advanced LPCN 2401 for obesity management, with Phase 2 study in GLP-1 eligible patients to begin Q3 2025.

  • Commercialization of TLANDO (oral testosterone) through multiple licensing agreements in the US, Canada, South Korea, GCC, and Brazil, with milestone and royalty revenue potential.

  • Seeking partners for further development and commercialization of pipeline assets.

Financial highlights

  • Q2 2025 revenue was $623K, up from $90K in Q2 2024, driven by $500K license revenue and $123K royalty revenue.

  • Net loss for Q2 2025 was $2.2M ($0.41/share), improved from $3.1M ($0.57/share) in Q2 2024; six-month net loss was $4.1M ($0.76/share) vs. net income of $445K ($0.10/share) in prior year, which included a $7.5M license payment.

  • R&D expenses rose to $2.1M in Q2 2025, mainly due to LPCN 2401 study initiation; G&A expenses fell to $0.9M.

  • Cash, cash equivalents, and marketable securities totaled $17.9M as of June 30, 2025, down from $21.6M at year-end 2024.

Outlook and guidance

  • Current capital resources expected to fund operations through at least August 2026, including ongoing clinical trials.

  • Topline results for LPCN 1154 Phase 3 trial expected Q2 2026; NDA submission planned for mid-2026.

  • Additional capital will be needed for expanded development or if milestones are not met; potential sources include equity, debt, or out-licensing.

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Frequently asked questions

Lipocine Inc. is a biopharmaceutical company focused on the development of oral drug delivery technologies for treating metabolic and endocrine disorders. The company specializes in hormone therapeutics, leveraging its proprietary Liprocol technology to enhance drug absorption and bioavailability. Lipocine's pipeline includes treatments for conditions such as testosterone deficiency, liver disease, and neuroendocrine disorders. The company is headquartered in Salt Lake City, Utah, and its shares are listed on the NASDAQ.

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