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Lisata Therapeutics (LSTA) investor relations material

Lisata Therapeutics Corporate Presentation summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Corporate Presentation summary21 Oct, 2025

Company overview and leadership

  • Clinical-stage pharmaceutical company focused on innovative therapies for cancer and serious diseases.

  • Mission to rapidly develop and commercialize treatments that improve patient outcomes.

  • Seasoned management team with global drug development and approval experience.

  • Proprietary technology with global IP protection extending beyond 2040.

  • Cash runway extends into Q1 2027 with no debt.

Therapeutic focus and scientific rationale

  • Solid tumors represent over 90% of diagnosed cancers, with high unmet need in pancreatic cancer.

  • Certepetide (iRGD peptide) targets and penetrates tumor stroma, enhancing drug delivery and modifying the tumor microenvironment.

  • Demonstrated ability to deplete immunosuppressive T cells and recruit cytotoxic T cells.

  • Broad preclinical evidence of improved survival and tumor response across multiple cancer types.

  • Strong IP portfolio with orphan drug designations and market exclusivity in US/EU.

Clinical results and development progress

  • Two Phase 1b/2a trials in metastatic PDAC showed improved overall survival with certepetide plus standard chemotherapy.

  • ASCEND Phase 2b trial: Cohort A showed numerically higher OS (12.68 vs 9.23 months); Cohort B mPFS neared statistical significance (7.46 vs 5.29 months, HR 0.61, p=0.09).

  • Certepetide demonstrated a benign safety profile, with adverse events consistent with companion therapies.

  • Early clinical data in combination with immunotherapy (durvalumab) in locally advanced PDAC showed high response and disease control rates.

  • Evidence of activity in other solid tumors, including sustained complete response in metastatic gastroesophageal adenocarcinoma.

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Q3 202511 Nov, 2025
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Q3 202511 Nov, 2025

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Frequently asked questions

Lisata Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative cell-based therapies for the treatment of advanced-stage diseases. The company's research and development efforts are primarily centered on addressing unmet medical needs in oncology, cardiovascular, and other serious conditions. Lisata leverages its proprietary technologies to create therapeutic solutions that promote tissue repair and regeneration. The company serves the healthcare sector with a focus on advancing treatments in areas where current options are limited. The company is headquartered in Basking Ridge, New Jersey, and its shares are listed on the NASDAQ.

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