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Lisata Therapeutics (LSTA) investor relations material

Lisata Therapeutics Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary7 Aug, 2025

Executive summary

  • Achieved key clinical and corporate milestones, including new research agreements and strategic alliances in Q2 2025.

  • Focused on developing certepetide, a novel agent for solid tumors, with multiple ongoing global Phase 2 trials and promising preliminary results from ASCEND and iLSTA.

  • Leadership team has extensive biopharma experience; strategy includes pipeline advancement and out-licensing.

  • Cash runway extends into Q4 2026, supporting all current clinical programs through next data milestones.

  • Multiple ongoing and planned clinical studies with anticipated data-rich period over the next 12 months.

Financial highlights

  • Q2 2025 revenue was $70,000 from an upfront license agreement with Catalent; no revenue in Q2 2024.

  • Operating expenses decreased 10.6% year-over-year to $4.9M, mainly due to lower R&D and G&A costs.

  • Net loss for Q2 2025 was $4.7M, down from $5.0M in Q2 2024; net loss for six months was $9.4M, down from $10.4M.

  • Cash, equivalents, and marketable securities totaled $22M as of June 30, 2025, supporting operations into 2026.

  • Working capital was $20.6M and stockholders' equity was $21.0M at quarter end.

Outlook and guidance

  • Cash and marketable securities expected to fund operations for at least the next 12 months and into Q4 2026.

  • Anticipates a data-rich 12 months with several key clinical milestones and readouts from ASCEND, BOLSTER, CENDIFOX, and iLSTA trials.

  • Additional financing likely needed by late 2026 for long-term needs; company seeks non-dilutive funding and partnerships.

  • Ongoing clinical trials progressing as planned, but some new studies remain on hold to manage capital.

  • $10M milestone payment expected upon Qilu's progression of certepetide to Phase 3 in China.

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Frequently asked questions

Lisata Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative cell-based therapies for the treatment of advanced-stage diseases. The company's research and development efforts are primarily centered on addressing unmet medical needs in oncology, cardiovascular, and other serious conditions. Lisata leverages its proprietary technologies to create therapeutic solutions that promote tissue repair and regeneration. The company serves the healthcare sector with a focus on advancing treatments in areas where current options are limited. The company is headquartered in Basking Ridge, New Jersey, and its shares are listed on the NASDAQ.

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