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MaaT Pharma (MAAT) investor relations material

MaaT Pharma H1 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H1 2025 earnings summary17 Sep, 2025

Executive summary

  • Advanced clinical-stage biotech focused on microbiome therapies for cancer and immune modulation, with two lead candidates (Xervyteg®/MaaT013 and MaaT033) in late-stage development.

  • Achieved major milestones: positive Phase 3 results for Xervyteg® in aGvHD, EMA submission, and exclusive EU commercialization deal with Clinigen, securing €10.5M upfront and up to €18M in milestones.

  • Secured €13M capital increase and €37.5M EIB financing to support clinical and commercial activities.

  • Expanded leadership team, increased free float, and inclusion in major Euronext Paris indices.

Financial highlights

  • Revenue for H1 2025: €2.4M, up 41% year-over-year, mainly from compassionate use of Xervyteg®.

  • Operating loss widened to €14.7M (vs. €12.7M or €12.8M in H1 2024); net loss at €15.1M (vs. €12.9M in H1 2024).

  • Operating expenses rose 20% to €19.7M, driven by R&D and clinical trial expansion.

  • Cash and equivalents at €15M as of June 30, 2025, excluding recent financing and partnership payments.

  • Cash runway extended to end of February 2026 with additional funds from Clinigen and EIB.

Outlook and guidance

  • Funding secured to operate through February 2026, with additional liquidity needs estimated at €24M to reach September 2026.

  • Key regulatory and clinical milestones expected in H2 2025 and 2026, including EMA approval for Xervyteg® and Phase 2/3 trial readouts.

  • Final 12-month overall survival data from the pivotal ARES study expected by end of 2025.

  • Potential EMA marketing authorization for Xervyteg® anticipated around mid-2026, with commercialization in Europe in H2 2026.

  • U.S. pivotal study for Xervyteg® under discussion, with possible initiation in 2026, subject to regulatory and financing conditions.

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Q3 2025 TU4 Nov, 2025
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Frequently asked questions

MaaT Pharma SA is a biotechnology company specializing in the development of microbiome-based therapies for the treatment of diseases related to immune and gastrointestinal disorders. The company focuses on restoring gut microbiota balance to support patient health, particularly in areas such as oncology and infectious diseases. MaaT Pharma utilizes a proprietary research platform to develop therapeutic solutions, including biotherapeutic products derived from microbiota. The company is engaged in clinical research and collaborates with healthcare institutions and industry partners to advance its pipeline. MaaT Pharma is headquartered in Lyon, France, and its shares are listed on the Euronext.

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