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Marker Therapeutics (MRKR) investor relations material

Marker Therapeutics Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary14 Nov, 2025

Executive summary

  • Focused on developing non-genetically engineered T cell immunotherapies for hematological malignancies and solid tumors, with lead programs in lymphoma and pancreatic cancer.

  • Phase 1 APOLLO study for MT-601 in lymphoma showed a 66% objective response rate and 50% complete response rate in relapsed NHL, with durable responses and favorable safety profile.

  • Manufacturing partnerships expanded, including a cGMP collaboration with Cellipont Bioservices for MT-601 scale-up.

  • First patient treated in the Off-the-Shelf (OTS) RAPID study for AML/MDS, with encouraging preliminary safety data and non-dilutive funding support.

  • Raised $10 million through ATM facility, extending cash runway into 2026.

Financial highlights

  • Grant income was $1.2M for Q3 2025, down 36% year-over-year; $2.4M for the nine months, down 44% year-over-year.

  • Cash, cash equivalents, and restricted cash totaled $18.9M as of September 30, 2025.

  • R&D expenses decreased to $2.3M from $3.5M YoY for the quarter; G&A expenses were $1M, up from $0.9M YoY.

  • Net loss for Q3 2025 was $2.0M (improved from $2.3M YoY); for the nine months, $10.5M (worsened from $6.9M YoY).

  • Net loss per share for Q3 2025: $(0.12); for nine months: $(0.75).

Outlook and guidance

  • Current cash position expected to fund operations through Q3 2026, assuming no additional grant funds.

  • Additional clinical data from APOLLO study and MT-601 pancreatic cancer program launch anticipated in the first half of 2026.

  • Management is seeking additional capital and grant funding to extend runway beyond Q3 2026.

  • Anticipates continued net losses as R&D and clinical activities expand.

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Frequently asked questions

Marker Therapeutics Inc is a U.S.-based biotechnology company focused on the development of immunotherapies for cancer. The company’s therapeutic approach involves multi-tumor antigen-specific T cell therapies that are designed to target various hematological and solid tumors. It conducts clinical trials and research collaborations to advance its cell therapy platforms. It is headquartered in Houston, Texas, and its shares are listed on the NASDAQ.

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