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Medivir (MVIR) investor relations material
Medivir Life Science Summit 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Life Science Summit 2025 summary17 Nov, 2025
Key developments and clinical progress
Advancing the first liver-targeted treatment for advanced liver cancer, with promising early-stage data and a move to a randomized phase II study of 80 patients.
The rights issue is fully guaranteed and aims to fund the phase II study, with the subscription period opening soon.
FOSTROX, a liver-targeted oral chemotherapy, is combined with a kinase inhibitor to address the unmet need in second-line advanced liver cancer.
Early studies show over 75% of patients experienced tumor shrinkage, with a median time to progression of 10.9 months, outperforming LENVIMA monotherapy.
The upcoming phase II study will compare FOSTROX plus LENVIMA to LENVIMA alone, with patient enrollment targeted for early 2026 and data expected by mid-2027.
Market opportunity and competitive landscape
The second-line advanced liver cancer market is projected to grow rapidly, with a conservative annual value estimate of $3 billion.
No approved or funded second-line treatment options currently exist, highlighting a significant unmet need.
Most competitors focus on first-line immunotherapy combinations, with little development in second-line therapies.
FOSTROX’s unique mechanism and combination approach position it as a potential first-mover in this space.
Patent protection for the FOSTROX and LENVIMA combination has been secured in Europe and Japan, with further approvals anticipated.
Strategic focus and future plans
The primary strategic goal is to complete the phase II study and move into a registrational program if results are positive.
Enrollment for the phase II study is expected to last 12 months, with the first data readout anticipated in mid-2027.
Out-licensing of non-core assets, such as remetinostat, continues to generate additional value without diverting focus from FOSTROX.
The company remains committed to liver cancer, delegating other assets to external partners for development.
Patent strategy is a key element to maintain competitive advantage and market exclusivity.
Competitive advantage in 2nd line liver cancer
Rationale for Phase 2 study design choices
FOSTROX combination patent's strategic value
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Next Medivir earnings date
Q4 202518 Feb, 2026
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Frequently asked questions
Medivir AB researches, develops, and sells pharmaceuticals primarily for the treatment of oncology in Sweden and internationally. It focuses on targeted therapies and vaccines. The company offers Merivo alfa, a product that has completed late stage clinical trials; MIV-711, which has completed phase I/II clinical trials; MIV-102 that has completed phase I/II clinical trial; and other projects in various phases of clinical development. Medivir AB was founded in 1987 and is headquartered in Huddinge, Sweden.
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