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Merck & Co (MRK) investor relations material

Merck & Co Citi Annual Global Healthcare Conference 2025 summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Citi Annual Global Healthcare Conference 2025 summary3 Dec, 2025

Influenza and Cidara deal

  • CD388 antiviral offers strain-agnostic, once-per-season protection, targeting high-risk and immunocompromised populations with 76% efficacy in phase three dosing.

  • Commercial opportunity estimated at over $5 billion by early 2030s, with 110 million U.S. candidates, 85 million of whom are high-risk.

  • Payer research suggests $500–$600 per dose is seen as good value for high-risk groups.

  • Phase three trials will include both vaccinated and unvaccinated high-risk individuals, focusing on endpoints like hospitalizations and severity.

Verona acquisition and Ohtuvayre

  • Ohtuvayre, a non-steroidal anti-inflammatory for COPD, is positioned favorably in GOLD guidelines and has received excellent market feedback.

  • Plans to leverage existing commercial infrastructure and digital capabilities to scale Ohtuvayre’s reach.

  • Exploring additional indications such as non-cystic fibrosis bronchiectasis.

WINREVAIR and pulmonary hypertension

  • CADENCE trial in left heart disease (HFpEF) showed clear proof-of-concept data; phase three to start next year with regulatory discussions ongoing.

  • WINREVAIR in PAH is seeing strong uptake, especially in triple and dual therapy segments, with durable efficacy and positive real-world feedback.

  • International launches underway, with encouraging starts in Japan and Europe.

  • Auto-injector expected next year to improve patient convenience and adoption.

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Frequently asked questions

Over 130 Years of Experience in Healthcare

Merck & Co., commonly known as Merck, is a global pharmaceutical company that specializes in the development and manufacturing of prescription drugs, vaccines, biological therapies, and animal health products. With a storied history dating back over a century, Merck has established itself as a leading player in the healthcare industry. The company's portfolio of products spans various therapeutic areas, including cardiovascular, oncology, infectious diseases, and more.

In business for over a century

Since its establishment in 1891, Merck has played a significant role in advancing medical research and innovation and has a long history of notable contributions to healthcare. They have developed antibiotics like streptomycin, vaccines for diseases such as mumps and HPV, and antiretroviral therapies for HIV/AIDS treatment. Their advancements in cardiovascular medications and statins have significantly impacted heart disease management.

The company today

Today the company focuses on the development, manufacturing, and distribution of a diverse range of prescription drugs, vaccines, and biological therapies. With a commitment to scientific rigor, research, and providing products and medication that improve the lives of ill patients, Merck strives to address various health challenges and contribute to the well-being of individuals globally. Merck is far from being alone when it comes to publicly traded pharmaceutical companies, and some companies that operate in the same space include names such as Pfizer and Eli Lilly.

A diverse portfolio of medications

Merck & Co. develops and manufactures a wide range of medications. Their portfolio of products includes medications for cardiovascular diseases, such as hypertension and hyperlipidemia, as well as anticoagulants and antiplatelet agents. They also offer therapeutics for infectious diseases, including antibiotics, antifungals, and antiviral drugs. In oncology, Merck provides targeted therapies and immunotherapies for different types of cancer. Additionally, they offer medications for diabetes management, respiratory diseases, autoimmune disorders, and more. The company’s flagship medication is Keytruda, which enhances the body’s ability to fight certain types of cancers.

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