)

Merus (MRUS) investor relations material
Merus Wells Fargo 20th Annual Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Platform and pipeline overview
Focus on oncology with a portfolio of clinical assets, including partnerships with major pharma companies.
Bispecific antibody platform enables development of innovative therapies, leveraging established monoclonal antibody processes.
Platform supports compatibility with standard antibody drug conjugate technologies.
Three out of four clinical-stage assets show improved clinical success rates, including Biclonics® and petosemtamab.
Petosemtamab in colorectal cancer
Petosemtamab targets EGFR and LGR5, with preclinical data showing strong activity in colorectal cancer models.
LGR5 is expressed in a subset of colorectal cancer cells, believed to drive tumor growth and metastasis.
Early phase 1 data in heavily pretreated colorectal cancer patients showed no responses, prompting a shift to earlier-line, genetically wild-type cohorts.
Ongoing studies include three cohorts: first-line with chemo, second-line with chemo, and third-line monotherapy, with a clinical update expected in the second half of the year.
Benchmarks for efficacy are based on cetuximab response rates (65% first-line, 30% second-line).
Petosemtamab in head and neck cancer
Robust efficacy and safety data in both first- and second-line recurrent/metastatic head and neck cancer.
First-line combination with pembrolizumab showed a 63% response rate and nearly 80% one-year survival, surpassing historical standards.
Second-line monotherapy demonstrated a 36% response rate and median survival of 12.5 months, with favorable safety.
Breakthrough therapy designation granted by FDA for both first- and second-line settings.
Phase 3 registration trials ongoing, designed for potential accelerated approval under Project FrontRunner framework.
Next Merus earnings date

The essential earnings season companion
The #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Live calls and transcripts
Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.
Find what you need faster
Search for any keyword across all transcripts simultaneously.
Easily store key findings
Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Your watchlist. Your dashboard.
Follow the companies that matter to you. Get a personalized feed with real-time updates.
Be the first to know
Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.
Consensus estimates
Access analyst consensus estimates, valuation multiples, and revenue segments splits.
All IR material in one place
The easiest way to stay updated during earnings season.
Global coverage
All events from public companies. Live and recorded.
Just click and listen
No webcast links. No manual registrations.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
)
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
)
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
)
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
)
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
)
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
)
I can't remember the last time an app had such a positive impact on my investment process.
)
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
)
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
)
I can't remember the last time an app had such a positive impact on my investment process.
)
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
)
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
)
)
)
)
Frequently asked questions
Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.
Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.
Explore our global coverage