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Metsera Inc (MTSR) investor relations material
Metsera Inc Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary12 Nov, 2025
Executive summary
Entered into a definitive merger agreement with Pfizer, valuing equity at ~$10 billion, with $65.60/share in cash plus contingent value rights (CVRs) for milestone achievements; closing expected in Q4 2025, pending regulatory approvals.
Completed IPO in February 2025, raising $288.4 million in net proceeds; significant capital raised from preferred stock prior to IPO.
Lead candidate MET-097i showed positive Phase 2b results (14.1% weight loss at 28 weeks) and strong tolerability; Phase 3 initiation planned for late 2025.
Financial highlights
Net loss of $116.2 million for Q3 2025 and $261.5 million for the nine months ended September 30, 2025, compared to $109.6 million and $156.3 million for the same periods in 2024.
Research and development expenses increased to $63.7 million for Q3 2025 (up $33.8 million YoY) and $181.4 million for the nine months (up $112.8 million YoY), driven by clinical program ramp-up and personnel costs.
General and administrative expenses rose to $15.0 million for Q3 2025 (up $7.7 million YoY) and $35.1 million for the nine months (up $18.1 million YoY), mainly due to higher personnel and stock-based compensation.
Cash and cash equivalents were $448.5 million as of September 30, 2025.
Outlook and guidance
Existing cash expected to fund operations for at least 12 months from the reporting date.
Anticipates continued significant operating losses as clinical programs advance and pipeline expands.
If the merger is not completed, substantial additional capital will be required to fund ongoing operations.
Pfizer merger litigation status and TRO outcome?
MET-097i's differentiated profile vs. competitors?
Amneal facility funding and operational risks?
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Next Metsera Inc earnings date
Q4 202526 Mar, 2026
Next Metsera Inc earnings date
Q4 202526 Mar, 2026
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