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Minerva Neurosciences (NERV) investor relations material

Minerva Neurosciences Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary14 Aug, 2025

Executive summary

  • Focused on proprietary CNS therapies, with lead candidate roluperidone for schizophrenia and MIN-301 for Parkinson's disease; no commercialized products or revenue to date.

  • FDA issued a Complete Response Letter for roluperidone, requiring a new 52-week confirmatory trial before resubmission, impacting regulatory timelines.

  • Strategic alternatives are under review due to cash constraints and regulatory requirements.

  • Accumulated deficit reached $402.4 million as of June 30, 2025; net loss for the six months ended June 30, 2025 was $7.0 million, improved from $16.8 million year-over-year.

Financial highlights

  • Cash, cash equivalents, and restricted cash totaled $15.3 million as of June 30, 2025, down from $21.5 million at year-end 2024.

  • Net loss for Q2 2025 was $3.3 million ($0.43/share), improved from $6.3 million ($1.09/share) in Q2 2024.

  • Research and development expenses decreased to $1.3 million in Q2 2025 from $3.9 million in Q2 2024; six-month R&D was $2.7 million vs $8.0 million prior year.

  • General and administrative expenses fell to $2.1 million in Q2 2025 from $2.4 million in Q2 2024; six-month G&A was $4.6 million vs $4.9 million prior year.

  • No revenue generated from product sales or licenses; all income derived from investment and royalty arrangements.

Outlook and guidance

  • Existing cash is not sufficient to fund operations and capital requirements beyond the next twelve months; cost reduction initiatives are underway.

  • Additional capital will be required to advance clinical programs and support operations; strategic alternatives, including partnerships or transactions, are under review.

  • Uncertainty remains regarding the timing and outcome of the required confirmatory trial for roluperidone and future regulatory approvals.

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Frequently asked questions

Minerva Neurosciences Inc is a biopharmaceutical company focused on the development of therapies for central nervous system disorders. The company's research targets conditions such as schizophrenia, depression, and insomnia through proprietary drug candidates. Minerva Neurosciences collaborates with academic and industry partners to advance its clinical programs. The company is headquartered in Burlington, Massachusetts, and its shares are listed on the NASDAQ.

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