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Monopar Therapeutics (MNPR) investor relations material
Monopar Therapeutics Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary13 Nov, 2025
Executive summary
Clinical-stage biopharma advancing ALXN1840 for Wilson disease and MNPR-101 radiopharmaceuticals, with multiple clinical and preclinical programs active as of Q3 2025.
ALXN1840 pivotal Phase 3 met primary endpoint; NDA submission to FDA planned for early 2026.
Presented new long-term efficacy and safety data for ALXN1840 at major medical conferences, highlighting neurological and hepatic benefits.
Received FDA clearance for IND application of MNPR-101-Lu for advanced or metastatic solid tumors.
Recent capital raise in September 2025 netted $91.9 million after share repurchase, extending cash runway through at least December 2027.
Financial highlights
Cash, cash equivalents, and investments totaled $143.7 million as of September 30, 2025.
Net loss for Q3 2025 was $3.44 million, compared to $1.30 million in Q3 2024; nine-month net loss was $8.52 million, up from $4.66 million year-over-year.
R&D expenses rose to $2.59 million in Q3 2025 (up $1.61 million YoY), mainly due to ALXN1840 manufacturing and increased personnel costs.
G&A expenses increased to $1.50 million in Q3 2025 (up $0.91 million YoY), driven by higher board compensation and personnel costs.
Interest income increased significantly due to higher cash balances from the capital raise.
Outlook and guidance
Current funds expected to support operations through at least December 2027, covering NDA submission for ALXN1840 and advancement of radiopharmaceutical pipeline.
No revenue expected until regulatory approval and commercialization of a product candidate.
Expenses anticipated to increase as clinical and preclinical programs progress.
ALXN1840's competitive edge in Wilson disease?
Linker tech's impact on MNPR-101 pipeline?
Rationale for Tactic Pharma share repurchase?
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Next Monopar Therapeutics earnings date
Q4 202526 Mar, 2026
Next Monopar Therapeutics earnings date
Q4 202526 Mar, 2026
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