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NeuroScientific Biopharmaceuticals (NSB) investor relations material
NeuroScientific Biopharmaceuticals Investor presentation summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Corporate and capital snapshot
As at November 2026: share price A$0.05; market capitalisation ~A$19.5m; cash ~A$3.9m at 30 September 2026.
Capital structure: 389.72m ordinary shares, 1.50m performance shares and 43.25m options.
Market opportunity and positioning
Global Crohn’s disease market cited at US$13B+; 6–8m patients globally, with 30% not responding to standard therapies.
StemSmart targets patients who have failed at least two mechanisms, positioning it as a new therapy line after biologic failure.
Fistulising disease can cause severe complications, and surgery may become inevitable when treatment options are limited.
StemSmart technology and clinical evidence
Purpose-built mesenchymal stem cell therapy for severe inflammation; proprietary activation process, patented technology and production under TGA accreditation.
Open-label Phase 2 luminal study in 18 anti-TNF-refractory patients reported 78% clinical response, 44% remission and 44% endoscopic improvement at Day 42.
Crohn’s Special Access results in fistulising patients reported an 80% response rate in five adults; CDAI, PDAI and IBDQ improved in all five, with MRI trending toward fistula healing.
Prior studies reported no serious adverse events attributed to MSCs; the Phase 2 study was single-arm and had no placebo control.
- FDA feedback cleared key trial questions as StemSmart Phase 2 preparation advanced.NSB
Q1 2027 TU - Net loss widened to $4.7M as R&D spending rose, despite a 279% income increase from incentives.NSB
H2 2026 - StemSmart showed 80% efficacy in Crohn's Disease, with strong cash reserves and Phase 2 trials planned.NSB
Q4 2026 TU - StemSmart showed strong efficacy in Crohn's, with two phase II trials set to start by year-end.NSB
Status update - StemSmart shows strong early efficacy in Crohn's, with Phase 2 trials and scale-up on track.NSB
Q3 2026 TU - StemSmart™ delivers promising clinical results for refractory Crohn's, advancing to Phase 2 trials.NSB
Investor presentation - Returned to profitability in FY2024 with $324,210 net profit and strong cash reserves for R&D.NSB
H2 2024 - Net loss widened to $1.7M as R&D accelerated, with cash reserves supporting continued development.NSB
H1 2026 - StemSmart™ MSC platform shows strong clinical promise and is advancing toward global Phase 2 trials.NSB
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