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Novartis (NOVN) investor relations material

Novartis Q4 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 earnings summary4 Feb, 2026

Executive summary

  • Achieved 8% year-over-year net sales growth to $54.5B and 14% increase in core operating income for FY 2025, with a record 40.1% core margin two years ahead of plan.

  • Priority brands Kisqali, Kesimpta, Pluvicto, Scemblix, Leqvio, and Cosentyx delivered robust double-digit growth, offsetting US generic erosion.

  • Advanced pipeline with multiple regulatory submissions, FDA/EC approvals, and positive Phase III data; strategic acquisition of Avidity Biosciences announced.

  • Record free cash flow of $17.6B (CHF 17.6B), up 8% year-over-year.

  • Completed CHF 15B share buyback, launched new CHF 10B program, and proposed 29th consecutive dividend increase to CHF 3.70/share.

Financial highlights

  • Full-year net sales up 8% to $54.5B; core operating income up 14% to $21.9B.

  • Core margin reached 40.1% (+2.1 pts); free cash flow $17.6B (+8%).

  • Core EPS up 17% to $8.98; reported EPS up 22% to $7.21.

  • Q4 net sales $13.3B (+1%); Q4 core operating income $4.9B (+1%), margin 37.0%.

  • Net debt increased to $21.9B at year-end.

Outlook and guidance

  • 2026 net sales expected to grow low single-digit; core operating income to decline low single-digit due to US generics and Avidity deal dilution.

  • H1 2026 to be most impacted by US generics; recovery expected in H2.

  • Mid-term sales CAGR of 5-6% (2025-2030) reaffirmed, with core margin expected to return to 40%+ by 2029.

  • FX expected to have a positive 2-3 percentage point impact on 2026 sales.

  • Dividend of CHF 3.70 per share proposed for 2025, a 5.7% increase.

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Frequently asked questions

Swiss Pharmaceuticals

Novartis International AG is a Swiss multinational pharmaceutical corporation headquartered in Basel, Switzerland. Established in 1996 through the merger of two companies, Novartis has cemented its place as one of the world's largest and most influential pharmaceutical companies with operations in over 150 countries. The company's portfolio includes a range of medicines, generic drugs, eye care devices, and consumer health products.

Roots in Swiss Pharmaceutical Companies

Novartis can trace its roots in two Swiss chemical companies, Ciba-Geigy and Sandoz, which had both been active in the global pharmaceutical industry for over a century before their merger. The fusion in 1996 aimed to leverage their combined strength in research and development, resulting in a global pharmaceutical behemoth. Novartis has since consistently ranked among the largest healthcare companies globally, partly due to its strong commitment to the development of new treatments.

A Diversified Pharmaceutical Powerhouse

Novartis operates under three main divisions: Innovative Medicines, Sandoz (generics), and Alcon (eye care). The Innovative Medicines division also referred to as the pharmaceuticals division, is dedicated to developing, manufacturing, and marketing patented prescription drugs. It includes two business units: Novartis Oncology and Novartis Pharmaceuticals, which target various therapeutic areas, including oncology, cardiology, respiratory, neuroscience, and ophthalmology, to name a few. Sandoz, the generics division of Novartis, provides high-quality, affordable medicines that treat some of the most prevalent healthcare issues. Lastly, the Alcon division focuses on eye care, manufacturing medical devices and products for eye care professionals and patients. They operate in the same field as companies such as Roche, Sanofi, Pfizer, and other large pharmaceutical companies.

Keeping Up With the Times

While remaining at the forefront of pharmaceutical innovation, Novartis continuously aims to refine its product portfolio and adapt to the ever-evolving healthcare landscape. The company has made significant strides in gene and cell therapies, most notably with Kymriah, a CAR-T cell therapy for certain types of blood cancers. Moreover, Novartis is working in digital health, employing data science and digital technologies to aid in drug discovery, patient care, and even the way clinical trials are conducted. The goal is to make treatments more personalized and more efficient, further enhancing patient outcomes.

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