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Nxera Pharma (4565) investor relations material

Nxera Pharma Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary31 Oct, 2025

Executive summary

  • Technology-driven biopharma focused on specialty medicines in neurology, metabolic, and immunology/GI, with global and local operations and a strong presence in Japan and APAC.

  • Over 400 employees, 20+ partnered programs, and 1,500 patents granted; listed on Tokyo Stock Exchange PRIME.

  • Reported revenue of JPY 21,848 million for the nine months ended September 30, 2025, a slight decrease of 0.6% year-over-year.

  • Core operating loss was JPY 986 million, compared to a core operating profit of JPY 4,425 million in the prior year.

  • Strategic acquisitions and partnerships have built a robust pipeline and recurring revenue streams.

Financial highlights

  • FY2025 product sales guidance: JPY 13.0–14.0bn (PIVLAZ®) and JPY 4.0–5.0bn (QUVIVIQ®) from royalty and supply.

  • Revenue from marketed products rose 37.8% to JPY 13,784 million, driven by PIVLAZ® and QUVIVIQ®.

  • R&D expenses up 36% YoY; SG&A down 1% YoY.

  • Core operating income posted a loss due to a YoY decline in milestone revenue, despite commercial sales growth.

  • Cost of sales increased by JPY 657 million, primarily from QUVIVIQ® launch costs.

Outlook and guidance

  • FY2025 objectives: JPY 17bn+ net product sales, in-license at least one late-stage medicine, execute a major partnership, and achieve positive operating profit if GPR52 option is exercised.

  • R&D expenses guided at JPY 12–14bn; S&M and G&A at JPY 15–17bn, with cost savings expected.

  • No consolidated financial results forecast due to unpredictability of milestone and partnership revenues.

  • Focus on maximizing sales and profit for PIVLAZ® and QUVIVIQ®, and expanding late-stage in-licensing.

  • Anticipates new partnerships, milestone payments, and expansion of drug discovery efforts.

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Jefferies London Healthcare Conference 202517 Nov, 2025
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Frequently asked questions

Sosei Group Corporation, also known as Sosei Heptares, is a biopharmaceutical company that specializes in the development of drugs using its proprietary G protein-coupled receptor (GPCR) targeted StaR technology and structure-based drug discovery (SBDD) platform. The company's product lineup includes medicines such as Ultibro, Seebri, Enerzair, Breezhaler, Pivlaz, and Oravi. Sosei Group Corporation is headquartered in Chiyoda-ku, Tokyo, Japan, and its shares are listed on the Tokyo Stock Exchange.

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