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Nxera Pharma (4565) investor relations material
Nxera Pharma Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Technology-driven biopharma focused on specialty medicines in neurology, metabolic, and immunology/GI, with global and local operations and a strong presence in Japan and APAC.
Over 400 employees, 20+ partnered programs, and 1,500 patents granted; listed on Tokyo Stock Exchange PRIME.
Reported revenue of JPY 21,848 million for the nine months ended September 30, 2025, a slight decrease of 0.6% year-over-year.
Core operating loss was JPY 986 million, compared to a core operating profit of JPY 4,425 million in the prior year.
Strategic acquisitions and partnerships have built a robust pipeline and recurring revenue streams.
Financial highlights
FY2025 product sales guidance: JPY 13.0–14.0bn (PIVLAZ®) and JPY 4.0–5.0bn (QUVIVIQ®) from royalty and supply.
Revenue from marketed products rose 37.8% to JPY 13,784 million, driven by PIVLAZ® and QUVIVIQ®.
R&D expenses up 36% YoY; SG&A down 1% YoY.
Core operating income posted a loss due to a YoY decline in milestone revenue, despite commercial sales growth.
Cost of sales increased by JPY 657 million, primarily from QUVIVIQ® launch costs.
Outlook and guidance
FY2025 objectives: JPY 17bn+ net product sales, in-license at least one late-stage medicine, execute a major partnership, and achieve positive operating profit if GPR52 option is exercised.
R&D expenses guided at JPY 12–14bn; S&M and G&A at JPY 15–17bn, with cost savings expected.
No consolidated financial results forecast due to unpredictability of milestone and partnership revenues.
Focus on maximizing sales and profit for PIVLAZ® and QUVIVIQ®, and expanding late-stage in-licensing.
Anticipates new partnerships, milestone payments, and expansion of drug discovery efforts.
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